1,3-Difluoroacetone

Base Information

Chemical Name:1,3-Difluoroacetone
CAS No.:453-14-5
Molecular Formula:C3H4F2O
Molecular Weight:94.061
Hs Code.:2914700090
NSC Number:21301
DSSTox Substance ID:DTXSID00963363
Nikkaji Number:J146.983E
Wikidata:Q72462300
Mol file:453-14-5.mol

Synonyms:1,3-difluoroacetone

Suppliers and Price of 1,3-Difluoroacetone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,3-Difluoroacetone
100mg
$ 85.00

SynQuest Laboratories
1,3-Difluoroacetone 98%
5 g
$ 295.00

SynQuest Laboratories
1,3-Difluoroacetone 98%
1 g
$ 85.00

Sigma-Aldrich
1,3-Difluoroacetone 97%
1g
$ 97.90

Matrix Scientific
1,3-Difluoroacetone 98%
5g
$ 428.00

Matrix Scientific
1,3-Difluoroacetone 98%
1g
$ 90.00

Biosynth Carbosynth
1,3-Difluoroacetone
2 g
$ 320.00

Biosynth Carbosynth
1,3-Difluoroacetone
1 g
$ 200.00

Biosynth Carbosynth
1,3-Difluoroacetone
500 mg
$ 125.00

Biosynth Carbosynth
1,3-Difluoroacetone
10 g
$ 1040.00

Total 30 raw suppliers

Chemical Property of 1,3-Difluoroacetone

Chemical Property:

Refractive Index:n20/D1.371
Boiling Point:85.7°C at 760mmHg
Flash Point:22°C
PSA：17.07000
Density:1.092g/cm³
LogP:0.49450
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:94.02302107
Heavy Atom Count:6
Complexity:46.8

Purity/Quality:

99% ^*data from raw suppliers

1,3-Difluoroacetone ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 10-23/24/25
Safety Statements: 16-23-36/37/39-45

MSDS Files:

Useful:

Canonical SMILES:C(C(=O)CF)F
Uses 1,3-Difluoroacetone is used as pharmaceutical intermediate and for chemical research.

Technology Process of 1,3-Difluoroacetone

There total 7 articles about 1,3-Difluoroacetone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 453-13-4
1,3-difluoro-2-propanol

: 453-14-5
1,3-difluoro-propan-2-one

Guidance literature:: With potassium permanganate; copper(II) sulfate; In benzene; at 80 ℃; for 6h;
DOI:10.1055/s-1994-25552

Reference yield:

: mercury amalgam

: methoxyvinyl Sulfoxide

: 459-72-3
ethyl 2-fluoroacetate

: ammonium chloride

: 453-14-5
1,3-difluoro-propan-2-one

Guidance literature:: With n-butyllithium; magnesium sulfate; diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; aqueous THF; mercury (II) chloride; ethyl acetate;