3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one

Base Information

Chemical Name:3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one
CAS No.:40800-77-9
Molecular Formula:C10H11NOS
Molecular Weight:193.269
Hs Code.:
NSC Number:298295
DSSTox Substance ID:DTXSID50315954

Synonyms:40800-77-9;NSC 298295;3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one;NSC298295;SCHEMBL7836579;DTXSID50315954;3-methyl-3-(methylthio)indolin-2-one;NSC-298295;3-methyl-3-methylthioindol-2(3H)-one

Suppliers and Price of 3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one

Chemical Property:

Vapor Pressure:1.22E-05mmHg at 25°C
Boiling Point:369.1°Cat760mmHg
Flash Point:177°C
Density:1.23g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:193.05613515
Heavy Atom Count:13
Complexity:231

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2=CC=CC=C2NC1=O)SC

Technology Process of 3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one

There total 6 articles about 3-methyl-3-methylthio-1,3-dihydro-2H-indol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 79866-01-6
(N-phenyl)methyl(methylthio)ketenimine

: 201024-81-9
C,N-diphenylnitrone

: 40800-77-9
3-methyl-3-methylthioindol-2-one

Guidance literature:: In benzene; for 6h; Heating;
DOI:10.1039/P19810002727

Reference yield:

: 40800-64-4
3-methylsulfanyl-1,3-dihydroindol-2-one

: 74-88-4
methyl iodide

: 40800-77-9
3-methyl-3-methylthioindol-2-one

Guidance literature:: 3-methylsulfanyl-1,3-dihydroindol-2-one; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.666667h;

methyl iodide; In tetrahydrofuran;
DOI:10.1021/ja046690e

Reference yield:

: 62-53-3
aniline

: 40800-77-9
3-methyl-3-methylthioindol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuryl chloride / CH₂Cl₂ / 1.3 h / -78 °C

1.2: 2,6-lutidine / CH₂Cl₂ / 1 h / -78 °C

1.3: 64 percent / Et₃N / CH₂Cl₂ / -78 - 20 °C

2.1: NaH / dimethylformamide / 0.67 h / 20 °C

2.2: tetrahydrofuran

With sulfuryl dichloride; sodium hydride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja046690e