3-(Dimethylamino)-3'-methoxypropiophenone

Base Information

Chemical Name:3-(Dimethylamino)-3'-methoxypropiophenone
CAS No.:35076-32-5
Molecular Formula:C12H17 N O2
Molecular Weight:207.272
Hs Code.:2922509090
European Community (EC) Number:252-347-4
UNII:FC7T66Z59G
DSSTox Substance ID:DTXSID20188576
Nikkaji Number:J289.896I
Wikidata:Q83060381
ChEMBL ID:CHEMBL3545721
Mol file:35076-32-5.mol

Synonyms:3-(Dimethylamino)-3'-methoxypropiophenone;35076-32-5;EINECS 252-347-4;FC7T66Z59G;3-(dimethylamino)-1-(3-methoxyphenyl)propan-1-one;UNII-FC7T66Z59G;3-(Dimethylamino)-1-(3-methoxyphenyl)-1-propanone;1-Propanone, 3-(dimethylamino)-1-(3-methoxyphenyl)-;SCHEMBL2968636;CHEMBL3545721;DTXSID20188576;AKOS000265752;3-dimethylamino-1-(3-methoxyphenyl)-propan-1-one;3-Dimethylamino-1-(3-methoxyphenyl)propan-1-one

Suppliers and Price of 3-(Dimethylamino)-3'-methoxypropiophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Dimethylamino-1-(3-methoxyphenyl)propan-1-one
100mg
$ 485.00

TRC
3-Dimethylamino-1-(3-methoxyphenyl)propan-1-one
250mg
$ 1190.00

American Custom Chemicals Corporation
3-(DIMETHYLAMINO)-3'-METHOXYPROPIOPHENONE 95.00%
5MG
$ 498.39

Total 4 raw suppliers

Chemical Property of 3-(Dimethylamino)-3'-methoxypropiophenone

Chemical Property:

Boiling Point:305.4°Cat760mmHg
Flash Point:138.5°C
PSA：29.54000
Density:1.027g/cm³
LogP:1.82960
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:207.125928785
Heavy Atom Count:15
Complexity:204

Purity/Quality:

99% ^*data from raw suppliers

3-Dimethylamino-1-(3-methoxyphenyl)propan-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCC(=O)C1=CC(=CC=C1)OC
Uses 3-Dimethylamino-1-(3-methoxyphenyl)propan-1-one is an intermediate in the synthesis of Oxyfedrine (O870700), which acts as a vasodilator affecting the coronary base flow.

Technology Process of 3-(Dimethylamino)-3'-methoxypropiophenone

There total 4 articles about 3-(Dimethylamino)-3'-methoxypropiophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 506-59-2
N,N-dimethylammonium chloride

: 586-37-8
1-(3-Methoxyphenyl)ethanone

: 35076-32-5
1-(3'-methoxyphenyl)-3-(N,N-dimethylamino)-1-propanone

Guidance literature:: With hydrogenchloride; In ethanol; water; at 90 ℃; for 18h; Sealed tube;
DOI:10.1016/j.bmcl.2017.10.042

Reference yield: 72.4%

: 35076-32-5
1-(3'-methoxyphenyl)-3-(N,N-dimethylamino)-1-propanone

Guidance literature:: With hydrogenchloride; In ethanol; Reflux;

With sodium hydroxide; In water; at 0 ℃;

Reference yield:

: 30354-18-8
N,N-dimethyl(methylene)ammonium chloride

: 586-37-8
1-(3-Methoxyphenyl)ethanone

: 35076-32-5
1-(3'-methoxyphenyl)-3-(N,N-dimethylamino)-1-propanone

Guidance literature:: N,N-dimethyl(methylene)ammonium chloride; 1-(3-Methoxyphenyl)ethanone; In acetonitrile; at 3 - 25 ℃;

With sodium hydroxide; In water;