5-Iodoresorcinol

Base Information

• Chemical Name: 5-Iodoresorcinol
• CAS No.: 64339-43-1
• Molecular Formula: C6H5IO2
• Molecular Weight: 236.009
• Mol file: 64339-43-1.mol

Synonyms:1,3-Benzenediol, 5-iodo-;5-iodobenzene-1,3-diol;

Chemical Property of 5-Iodoresorcinol

Chemical Property:

• Melting Point: 92.5°C
• Boiling Point: 325.6±12.0 °C(Predicted)
• PKA: 8.60±0.10(Predicted)
• PSA: 40.46000
• Density: 1.9169 (estimate)
• LogP: 1.70240
• Solubility.: Ethyl Acetate, Methanol

Purity/Quality:

99% ^*data from raw suppliers

5-Iodoresorcinol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Iodoresorcinol

There total 11 articles about 5-Iodoresorcinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-iodo-3,5-dimethoxybenzene (25245-27-6) → 5-iodoresorcinol (64339-43-1)

Guidance literature:

With boron tribromide; In dichloromethane; at -20 - 20 ℃;

DOI:10.1016/0968-0896(96)00060-0

Reference yield:

3,5-dihydroxyphenylamine (20734-67-2) → 5-iodoresorcinol (64339-43-1)

Guidance literature:

3,5-dihydroxyphenylamine; With hydrogenchloride; In water;

With sulfuric acid; sodium nitrite; In water; at 0 ℃; for 0.25h;

With potassium iodide; In water; ethyl acetate; for 7h;

DOI:10.1055/s-0031-1289664

Reference yield:

3.5-dimethoxyaniline (10272-07-8) → 5-iodoresorcinol (64339-43-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaNO₂; HCl

1.2: KI

2.1: BBr₃

With hydrogenchloride; boron tribromide; sodium nitrite;

DOI:10.1021/jo060727r

upstream raw materials:

3-iodo-5-methoxyphenol

1-iodo-3,5-dimethoxybenzene

3,5-dimethoxy-1-phenylmagnesium chloride

1-bromo-3,5-dimethoxybenzene

Downstream raw materials:

3,5-dibenzyloxyphenyl iodide

(3-hydroxy-5-iodophenyl) 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

3,5-bis(4-toluenesulfonyloxy)iodobenzene

C₆H₅IO₂*C₂₃H₁₇N₃

Refernces

Hetero-double-helix formation by an ethynylhelicene oligomer possessing perfluorooctyl side chains

10.1021/jo8010057

The study focuses on the synthesis and characterization of ethynylhelicene oligomers with perfluorooctyl side chains, ranging from monomers to pentamers. Utilizing circular dichroism (CD) and vapor pressure osmometry (VPO), the research demonstrates the formation of a helix-dimer, particularly in the case of the pentamer within trifluoromethylbenzene at low temperatures and specific concentrations. A comparison between the perfluorooctyl and decyloxycarbonyl side-chained pentamers reveals that the former exhibits lower solubility in organic solvents, forms a more thermodynamically stable helix-dimer, and shows an inverted mirror image CD spectrum. Additionally, the perfluorooctyl pentamer is found to form a hetero-helix dimer with a decyloxycarbonyl pentamer, indicating a higher stability for the hetero-helix dimer over the homo-helix dimers. This work contributes to the understanding of double-helix structures in synthetic oligomers and their potential applications in supramolecular chemistry.