Acetamide, 2-chloro-N-[4-(3-methyl-3-phenylcyclobutyl)-2-thiazolyl]-

Base Information

Chemical Name:Acetamide, 2-chloro-N-[4-(3-methyl-3-phenylcyclobutyl)-2-thiazolyl]-
CAS No.:646997-61-7
Molecular Formula:C16H17ClN2OS
Molecular Weight:320.843
Hs Code.:
DSSTox Substance ID:DTXSID90450237

Synonyms:646997-61-7;Acetamide, 2-chloro-N-[4-(3-methyl-3-phenylcyclobutyl)-2-thiazolyl]-;DTXSID90450237

Suppliers and Price of Acetamide, 2-chloro-N-[4-(3-methyl-3-phenylcyclobutyl)-2-thiazolyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetamide, 2-chloro-N-[4-(3-methyl-3-phenylcyclobutyl)-2-thiazolyl]-

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:320.0750120
Heavy Atom Count:21
Complexity:381

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(C1)C2=CSC(=N2)NC(=O)CCl)C3=CC=CC=C3

Technology Process of Acetamide, 2-chloro-N-[4-(3-methyl-3-phenylcyclobutyl)-2-thiazolyl]-

There total 3 articles about Acetamide, 2-chloro-N-[4-(3-methyl-3-phenylcyclobutyl)-2-thiazolyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 79-04-9
chloroacetyl chloride

: 283604-98-8
4-(1-phenyl-1-methylcyclobutane-3-yl)-2-aminothiazole

: 646997-61-7
4-[1-methyl-1-phenylcyclobutane-3-yl]-2-(2-chloroacetamido)thiazole

Guidance literature:: With potassium carbonate; In benzene; for 4h;

Reference yield:

: 140428-71-3
1-methyl-1-phenyl-3-(2-chloro-1-oxoethyl)cyclobutane

: 646997-61-7
4-[1-methyl-1-phenylcyclobutane-3-yl]-2-(2-chloroacetamido)thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / ethanol / 50 - 60 °C

2: 76 percent / K₂CO₃ / benzene / 4 h

With potassium carbonate; In ethanol; benzene;

Reference yield:

: 2-chloro-1-(3-methyl-3-phenyl-cyclobutyl)-ethanol

: 646997-61-7
4-[1-methyl-1-phenylcyclobutane-3-yl]-2-(2-chloroacetamido)thiazole

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / Na₂Cr₂O₇; H₂SO₄

2: 70 percent / ethanol / 50 - 60 °C

3: 76 percent / K₂CO₃ / benzene / 4 h

With sodium dichromate; sulfuric acid; potassium carbonate; In ethanol; benzene;