4-Fluorobenzoyl chloride phenyl hydrazone

Base Information

• Chemical Name: 4-Fluorobenzoyl chloride phenyl hydrazone
• CAS No.: 25939-02-0
• Molecular Formula: C13H10 Cl F N2
• Molecular Weight: 248.687
• Hs Code.: 2928000090
• Mol file: 25939-02-0.mol

Synonyms:BRN 0959322;4-Fluorobenzoyl chloride phenyl hydrazone;BENZOYL CHLORIDE, p-FLUORO-, PHENYLHYDRAZONE;C13-H10-Cl-F-N2;25939-02-0;SCHEMBL9441604;LS-42606

Chemical Property of 4-Fluorobenzoyl chloride phenyl hydrazone

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 340.38°C at 760 mmHg
• Flash Point: 159.657°C
• PSA: 24.39000
• Density: 1.204g/cm³
• LogP: 3.91120
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 248.0516542
• Heavy Atom Count: 17
• Complexity: 256

Purity/Quality:

BENZOYL CHLORIDE P-FLUORO-, PHENYLHYDRAZONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NN=C(C2=CC=C(C=C2)F)Cl
• Isomeric SMILES: C1=CC=C(C=C1)N/N=C(/C2=CC=C(C=C2)F)\Cl

Technology Process of 4-Fluorobenzoyl chloride phenyl hydrazone

There total 7 articles about 4-Fluorobenzoyl chloride phenyl hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

1-(4-fluorobenzylidene)-2-phenylhydrazine (352-06-7) → 4-fluoro-N'-phenylbenzohydrazonoyl chloride (25939-02-0)

Guidance literature:

With N-chloro-succinimide; dimethylsulfide; In dichloromethane; at -78 ℃; for 2h; Inert atmosphere;

DOI:10.1002/chem.202001590

Reference yield:

4-fluoro-N′-phenylbenzohydrazide (1496-02-2) → 4-fluoro-N'-phenylbenzohydrazonoyl chloride (25939-02-0)

Guidance literature:

With tetrachloromethane; triphenylphosphine; In acetonitrile; at 20 ℃;

DOI:10.1111/j.1747-0285.2010.00948.x

Reference yield:

p-fluorobenzoic acid phenylhydrazide + phenol (108-95-2,27073-41-2) → 4-fluoro-N'-phenylbenzohydrazonoyl chloride (25939-02-0)

Guidance literature:

With phosphorus pentachloride; In tetrachloromethane;

upstream raw materials:

phenol

4-fluoro-N′-phenylbenzohydrazide

1-(4-fluorobenzylidene)-2-phenylhydrazine

4-fluorobenzaldehyde

Downstream raw materials:

4-Ethylsulfanyl-3-(4-fluoro-phenyl)-1,6-diphenyl-1H-[1,2,4]diazaphosphinine 4-sulfide

1,4-dihydro-4-thioxo-1,4,6-triphenyl-3-p-fluorophenyl-1,2,4-diazaphosphorine

4-Ethoxy-5-[1-ethylsulfanyl-meth-(E)-ylidene]-3-(4-fluoro-phenyl)-1-phenyl-1,5-dihydro-[1,2,4]diazaphosphole 4-oxide

C₃₃H₂₂Br₂FN₂O₂P