(2E)-3-[4-(Methylsulfonyl)phenyl]propenoic acid

Base Information Edit

Chemical Name:(2E)-3-[4-(Methylsulfonyl)phenyl]propenoic acid
CAS No.:88899-85-8
Molecular Formula:C₁₀H₁₀O₄S
Molecular Weight:226.253
Hs Code.:
European Community (EC) Number:826-800-7,674-448-6
Nikkaji Number:J854.718A
Mol file:88899-85-8.mol

Synonyms:5345-30-2;(2E)-3-[4-(Methylsulfonyl)phenyl]propenoic acid;3-(4-(methylsulfonyl)phenyl)acrylic acid;3-[4-(methylsulfonyl)phenyl]-(2e)-propenoic acid;88899-85-8;(E)-3-(4-methylsulfonylphenyl)prop-2-enoic acid;3-[4-(methylsulphonyl)phenyl]-(2e)-propenoic acid;(e)-3-(4-(methylsulfonyl)phenyl)acrylic acid;(2E)-3-(4-methanesulfonylphenyl)prop-2-enoic acid;(2E)-3-[4-(METHYLSULFONYL)PHENYL]PROPENOICACID;(2e)-3-(4-(methylsulfonyl)phenyl)propenoic acid;4-(Methylsulphonyl)cinnamic acid;3-(4-methanesulfonylphenyl)prop-2-enoic acid;HMS518N07;UDUXYCSLRYYQNS-QPJJXVBHSA-N;(E)-4-methylsulfonylcinnamic acid;AMY24918;MFCD00203126;(E)-3-(4-Mesylphenyl)propenoic acid;AKOS015852581;PS-5513;E87299;EN300-1991371;(E)-3-(4-methylsulfonylphenyl)-2-propenoic acid;A829602;SR-01000384285;SR-01000384285-1

Suppliers and Price of (2E)-3-[4-(Methylsulfonyl)phenyl]propenoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-(4-(methylsulfonyl)phenyl)acrylicacid 95
25g
$ 3447.00

Crysdot
(2E)-3-[4-(Methylsulfonyl)phenyl]propenoicacid 96%
10g
$ 743.00

Crysdot
(2E)-3-[4-(Methylsulfonyl)phenyl]propenoicacid 96%
5g
$ 427.00

Total 2 raw suppliers

Chemical Property of (2E)-3-[4-(Methylsulfonyl)phenyl]propenoic acid Edit

Chemical Property:

PSA：79.82000
LogP:2.26870
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:226.02997997
Heavy Atom Count:15
Complexity:342

Purity/Quality:

99% ^*data from raw suppliers

3-(4-(methylsulfonyl)phenyl)acrylicacid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)C1=CC=C(C=C1)C=CC(=O)O
Isomeric SMILES:CS(=O)(=O)C1=CC=C(C=C1)/C=C/C(=O)O

Technology Process of (2E)-3-[4-(Methylsulfonyl)phenyl]propenoic acid

There total 17 articles about (2E)-3-[4-(Methylsulfonyl)phenyl]propenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 141-82-2
malonic acid

: 5398-77-6
para-methanesulfonylbenzaldehyde

: 5345-30-2,88899-85-8
3-(4-methanesulfonyl-phenyl)-acrylic acid

Guidance literature:: With piperidine; In pyridine; at 95 - 100 ℃; for 4h;
DOI:10.1021/jo961479+

Reference yield: 77.0%

: 140134-65-2
(E)-3-<4-(methylthio)phenyl>propenoic acid

: 5345-30-2,88899-85-8
3-(4-methanesulfonyl-phenyl)-acrylic acid

Guidance literature:: With dihydrogen peroxide; acetic acid; at 90 - 95 ℃; for 1h;
DOI:10.1248/cpb.39.3236

Reference yield:

: 1879-16-9
1-methoxy-4-methylsulfanyl-benzene

: 5345-30-2,88899-85-8
3-(4-methanesulfonyl-phenyl)-acrylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / toluene / 1 h / Heating

2: 99 percent / aq. K₂CO₃ / methanol / 1 h / Heating

3: 77 percent / 30percent aq. H₂O₂, acetic acid / 1 h / 90 - 95 °C

With dihydrogen peroxide; potassium carbonate; acetic acid; In methanol; toluene;
DOI:10.1248/cpb.39.3236