Ethyl 3-hydroxyoctadecanoate

Base Information

Chemical Name:Ethyl 3-hydroxyoctadecanoate
CAS No.:65144-03-8
Molecular Formula:C20H40O3
Molecular Weight:328.536
Hs Code.:2918199090
DSSTox Substance ID:DTXSID40598971
Nikkaji Number:J46.051F
Mol file:65144-03-8.mol

Synonyms:ethyl 3-hydroxyoctadecanoate;65144-03-8;starbld0020508;Octadecanoic acid, 3-hydroxy-, ethyl ester;SCHEMBL7599629;DTXSID40598971;BXRPWBZYLZSTNL-UHFFFAOYSA-N

Suppliers and Price of Ethyl 3-hydroxyoctadecanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl3-Hydroxyoctadecanoate
1g
$ 860.00

Total 2 raw suppliers

Chemical Property of Ethyl 3-hydroxyoctadecanoate

Chemical Property:

PSA：46.53000
LogP:5.78180
XLogP3:7.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:18
Exact Mass:328.29774513
Heavy Atom Count:23
Complexity:253

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Ethyl3-Hydroxyoctadecanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCC(CC(=O)OCC)O
Uses Ethyl 3-Hydroxyoctadecanoate is an intermediate in the synthesis of 3-Hydroxystearoylcarnitine Hydrochloride (H953630), which is found in overweight patients.

Technology Process of Ethyl 3-hydroxyoctadecanoate

There total 6 articles about Ethyl 3-hydroxyoctadecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 62625-23-4
ethyl 3-oxooctadecanoate

: 65144-03-8
ethyl 3-hydroxyoctadecanoate

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 20 ℃;
DOI:10.1002/cmdc.201800720

Reference yield:

: 57-10-3
1-hexadecylcarboxylic acid

: 65144-03-8
ethyl 3-hydroxyoctadecanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere

1.2: 18 h / 20 °C / Inert atmosphere

2.1: sodium tetrahydroborate / ethanol / 20 °C

With sodium tetrahydroborate; 1,1'-carbonyldiimidazole; In tetrahydrofuran; ethanol;
DOI:10.1002/cmdc.201800720