diethyl 1-aMino-3-isopropyl-1H-pyrrole-2,4-dicarboxylate

Base Information

Chemical Name:diethyl 1-aMino-3-isopropyl-1H-pyrrole-2,4-dicarboxylate
CAS No.:651744-39-7
Molecular Formula:C13H20N2O4
Molecular Weight:268.313
Hs Code.:2933990090
Mol file:651744-39-7.mol

Synonyms:1-amino-3-(1-methylethyl)pyrrole-2,4-dicarboxylic acid dimethyl ester;DIETHYL-1(N)-AMINO-3-ISOPROPYL-PYRROLE-2,4-DICARBOXYLATE;DIETHYL 1-AMINO-3-ISOPROPYL-1H-PYRROLE-2,4-DICARBOXYLATE;

Suppliers and Price of diethyl 1-aMino-3-isopropyl-1H-pyrrole-2,4-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of diethyl 1-aMino-3-isopropyl-1H-pyrrole-2,4-dicarboxylate

Chemical Property:

PSA：83.55000
LogP:2.25990

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of diethyl 1-aMino-3-isopropyl-1H-pyrrole-2,4-dicarboxylate

There total 4 articles about diethyl 1-aMino-3-isopropyl-1H-pyrrole-2,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 651744-38-6
diethyl 3-(propan-2-yl)-1H-pyrrole-2,4-dicarboxylate

: 5137-55-3,76925-99-0
Aliquat 336

: 651744-39-7
diethyl 1-amino-3-(propan-2-yl)-1H-pyrrole-2,4-dicarboxylate

Guidance literature:: With ammonium hydroxide; sodium hypochlorite; ammonium chloride; sodium hydroxide; In tert-butyl methyl ether; water; at 20 ℃; for 72h;

Reference yield:

: 651744-38-6
diethyl 3-(propan-2-yl)-1H-pyrrole-2,4-dicarboxylate

: 651744-39-7
diethyl 1-amino-3-(propan-2-yl)-1H-pyrrole-2,4-dicarboxylate

Guidance literature:: With O-(diphenylphosphinyl)hydroxylamine; sodium hydride; In N,N-dimethyl-formamide; for 2h;
DOI:10.1021/jm0501275

Reference yield:

: 2999-46-4
Ethyl isocyanoacetate

: 651744-39-7
diethyl 1-amino-3-(propan-2-yl)-1H-pyrrole-2,4-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: DBU / tetrahydrofuran / 50 °C

2: O-(diphenylphosphinyl)-hydroxylamine; NaH / dimethylformamide

With O-(diphenylphosphinyl)hydroxylamine; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2005.07.027