Benzene, 1-bromo-4-(1-cyclopropylethenyl)-

Base Information

• Chemical Name: Benzene, 1-bromo-4-(1-cyclopropylethenyl)-
• CAS No.: 65322-32-9
• Molecular Formula: C11H11Br
• Molecular Weight: 223.112
• Mol file: 65322-32-9.mol

Synonyms:1-p-Bromphenyl-1-cyclopropylethen;1-p-Bromphenoxy-4-phenoxy-benzol;Benzene,1-(4-bromophenoxy)-4-phenoxy;4-bromo-1-(4-phenoxyphenoxy)benzene;

Chemical Property of Benzene, 1-bromo-4-(1-cyclopropylethenyl)-

Chemical Property:

• PSA: 0.00000
• LogP: 3.87230

Purity/Quality:

98.5% ^*data from raw suppliers

1-Bromo-4-(1-cyclopropylvinyl)benzene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 1-bromo-4-(1-cyclopropylethenyl)-

There total 5 articles about Benzene, 1-bromo-4-(1-cyclopropylethenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(4-bromophenyl)(cyclopropyl)methanone (6952-89-2) + Methyltriphenylphosphonium bromide (1779-49-3) → 1-bromo-4-(1-cyclopropylvinyl)benzene (65322-32-9)

Guidance literature:

Methyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 1h; Inert atmosphere;

(4-bromophenyl)(cyclopropyl)methanone; In tetrahydrofuran; hexane; at 40 ℃; for 12h; Inert atmosphere;

DOI:10.1021/acs.joc.6b01825

Reference yield: 85.0%

tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate + 4-methoxy-benzaldehyde (123-11-5) → 1-bromo-4-(1-cyclopropylvinyl)benzene (65322-32-9)

Guidance literature:

tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

4-methoxy-benzaldehyde; In tetrahydrofuran; for 1h; Inert atmosphere;

DOI:10.1002/anie.201610924

Reference yield:

1-(4-bromophenyl)-1-cyclopropylethan-1-ol (56041-75-9) → 1-bromo-4-(1-cyclopropylvinyl)benzene (65322-32-9)

Guidance literature:

DOI:10.1007/BF00923634

upstream raw materials:

1-(4-bromophenyl)-1-cyclopropylethan-1-ol

Cyclopropyl methyl ketone

(4-bromophenyl)magnesium bromide

(4-bromophenyl)(cyclopropyl)methanone

Downstream raw materials:

1-(4-Bromo-phenyl)-2,2-dichloro-bicyclopropyl