Quinoxaline-2,3-dicarbonitrile

Base Information

• Chemical Name: Quinoxaline-2,3-dicarbonitrile
• CAS No.: 17132-92-2
• Molecular Formula: C10H4 N4
• Molecular Weight: 180.169
• Hs Code.: 2933990090
• Mol file: 17132-92-2.mol

Synonyms:2,3-Dicyanoquinoxaline;NSC 160871

Chemical Property of Quinoxaline-2,3-dicarbonitrile

Chemical Property:

• Vapor Pressure: 4.8E-08mmHg at 25°C
• Melting Point: 210-215 °C
• Boiling Point: 443°Cat760mmHg
• PKA: -8.32±0.48(Predicted)
• Flash Point: 143.3°C
• PSA: 73.36000
• Density: 1.38g/cm³
• LogP: 1.37316

Purity/Quality:

99%min ^*data from raw suppliers

Quinoxaline-2,3-dicarbonitrile 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Quinoxaline-2,3-dicarbonitrile

There total 13 articles about Quinoxaline-2,3-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2,3-dichloroquinoxaline (2213-63-0) + tetraethylammoniumcyanide (13435-20-6) → quinoxaline-2,3-dicarbonitrile (17132-92-2)

Guidance literature:

In dimethyl sulfoxide; at 25 ℃; for 3h;

Reference yield: 53.0%

sodium cyanide (143-33-9,25596-52-5) + 3-chloro-2-quinoxalinecarbonitrile (40254-89-5) → quinoxaline-2,3-dicarbonitrile (17132-92-2)

Guidance literature:

In dimethyl sulfoxide; for 0.166667h; Ambient temperature;

DOI:10.1002/jhet.5570310506

Reference yield: 47.0%

trimethylsilyl cyanide (7677-24-9) + 2-(p-tolylsulfonyl)quinoxaline 4-oxide (128478-58-0) → quinoxaline-2,3-dicarbonitrile (17132-92-2)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 0 - 5 ℃; for 0.25h;

DOI:10.1248/cpb.38.661

upstream raw materials:

2,3-dichloroquinoxaline

tetraethylammoniumcyanide

3-chloroquinoxaline 1-oxide

trimethylsilyl cyanide

Downstream raw materials:

N′-(3-amino-1H-pyrrolo[3,4-b]quinoxalin-1-ylidene)-4-chlorobenzohydrazide

N′-(3-amino-1H-pyrrolo[3,4-b]quinoxalin-1-ylidene)benzohydrazide

N′-(3-amino-1H-pyrrolo[3,4-b]quinoxalin-1-ylidene)-4-fluorobenzohydrazide

N′-(3-amino-1H-pyrrolo[3,4-b]quinoxalin-1-ylidene)-2-phenylacetohydrazid

Refernces

• 1、 Hordiyenko, Olga V.,Rudenko, Igor V.,Zamkova, Irina A.,Denisenko, Oleksandr V.,Biitseva, Angelina V.,Arrault, Axelle,Tolmachev, Andrei A.. "Facile synthesis of hydrazine derivatives of 5H-pyrrolo[3,4-b]pyrazine and 1H-pyrrolo[3,4-b]quinoxaline". . p. 3375 - 3382. Retrieved 2014/01/06.
• 2、 Yanagi, Hisao,Kanbayashi, Yoshihiro,Schlettwein, Derck,Woehrle, Dieter,Amstrong, Neal R.. "Photoelectrochemical Investigations of Naphthalocyanine Derivatives in Thin Films". . p. 4760 - 4766. Retrieved 2007/10/02.