40254-89-5Relevant articles and documents
Synthesis and antituberculosis activity of some new 2-quinoxalinecarbonitriles.
Montoya,Sainz,Ortega,Lopez De Cerain,Monge
, p. 570 - 573 (1998)
Tuberculosis, an ancient disease undergoing recent control by public hygiene and drug therapy, has experienced a recrudescence throughout the world. New and effective therapies are rapidly needed to combat infections caused by these strains. Some new 2-quinoxalinecarbonitriles have been synthesized and tested as antituberculosis agents and interesting results have been obtained from the first screening.
Novel Antagonists of 5-HT3 Receptors. Synthesis and Biological Evaluation of Piperazinylquinoxaline Derivatives
Monge, A.,Palop, J. A.,Castillo, J. C. Del,Caldero, J. M.,Roca, J.,et al.
, p. 2745 - 2750 (2007/10/02)
A series of piperazinylquinoxalines has been synthesized and studied as 5-HT3 receptor antagonists in different preparations.Antagonism to 5-HT in the longitudinal muscle of the guinea pig ileum was particularly prominent in cyanoquinoxaline de
Quinoxalines. XXVII. The cyanation of 2-substituted quinoxaline 4-oxides with trimethylsilyl cyanide
Iijima,Miyashita
, p. 661 - 663 (2007/10/02)
The deoxy-cyanation of 2-substituted quinoxaline 4-oxides (1a--k) with trimethylsilyl cyanide in the presence of 1,8-diazabicyclo[5.4.0.]undec-7-ene gave the corresponding 3-substituted 2-quinoxalinecarbonitriles (IIa--k). However, in the case of 2-(p-tol
