Chemical Property of Ethyl caffeate
Chemical Property:
- Vapor Pressure:3.22E-06mmHg at 25°C
- Melting Point:147～151℃
- Refractive Index:1.612
- Boiling Point:377 °C at 760 mmHg
- PKA:8.71±0.18(Predicted)
- Flash Point:148.4 °C
- PSA：66.76000
- Density:1.271 g/cm3
- LogP:1.67410
- Storage Temp.:2-8°C
- XLogP3:2.6
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:4
- Exact Mass:208.07355886
- Heavy Atom Count:15
- Complexity:237
- Purity/Quality:
-
97% *data from raw suppliers
Ethyl 3,4-dihydroxycinnamate *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn
- Hazard Codes:Xn
- Statements:
36/37/38-22
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCOC(=O)C=CC1=CC(=C(C=C1)O)O
- Isomeric SMILES:CCOC(=O)/C=C/C1=CC(=C(C=C1)O)O
-
Uses
Ethyl 3,4-dihydroxycinnamate shows anti-inflammatory, immunomodulatory, and anti-carcinogenic properties. It is a potent and specific inhibitor of NF-κB and its downstream inflammatory mediators: NOS2 (inducible nitric oxide synthase; NOS; NOS II), Cox-2 (cyclooxygenase-2), and prostaglandin E2 (PGE2). Ethyl 3,4-Dihydroxycinnamate prevents DNA single-strand breaks caused by H2O2.
