2-[(E)-3-(4-methoxyphenyl)prop-2-enylidene]propanedioic acid

Base Information

Chemical Name:2-[(E)-3-(4-methoxyphenyl)prop-2-enylidene]propanedioic acid
CAS No.:6342-88-7
Molecular Formula:C₁₃H₁₂O₅
Molecular Weight:248.235
Hs Code.:
NSC Number:46659
DSSTox Substance ID:DTXSID90418039
Nikkaji Number:J550.071K

Synonyms:NSC46659;6342-88-7;DTXSID90418039;NSC-46659;3-(4-Methoxyphenyl)-2-propenylidenemalonic acid

Suppliers and Price of 2-[(E)-3-(4-methoxyphenyl)prop-2-enylidene]propanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-[(E)-3-(4-methoxyphenyl)prop-2-enylidene]propanedioic acid

Chemical Property:

Vapor Pressure:4.43E-12mmHg at 25°C
Boiling Point:530.4°Cat760mmHg
Flash Point:207.4°C
Density:1.33g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:248.06847348
Heavy Atom Count:18
Complexity:346

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=CC=C(C(=O)O)C(=O)O
Isomeric SMILES:COC1=CC=C(C=C1)/C=C/C=C(C(=O)O)C(=O)O

Technology Process of 2-[(E)-3-(4-methoxyphenyl)prop-2-enylidene]propanedioic acid

There total 6 articles about 2-[(E)-3-(4-methoxyphenyl)prop-2-enylidene]propanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1963-36-6
4-methoxycinnamaldehyde

: 141-82-2
malonic acid

: 6342-88-7
(4-methoxy-cinnamylidene)-malonic acid

Guidance literature:: With ammonium hydroxide; at 100 ℃;

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 6342-88-7
(4-methoxy-cinnamylidene)-malonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aqueous-methanolic NaOH-solution / 5 - 10 °C

2: glacial acetic acid / 50 - 60 °C

With sodium hydroxide; acetic acid;