10.1248/cpb.c16-00744
The study focuses on the development and application of acid-catalyzed allylating reagents based on triazine chemistry, specifically 2,4,6-tris(allyloxy)-1,3,5-triazine (TriAT-allyl) and its substituted derivatives. These reagents were used to synthesize allyl ethers and esters from various alcohols and carboxylic acids in the presence of a catalytic amount of trifluoromethanesulfonic acid (TfOH). The purpose of these chemicals is to provide a practical, high-yielding procedure for allylation, which is a method of introducing allyl groups into organic compounds. The allyl group is significant for protecting hydroxy and carboxy groups and can be used as monomer units in macromolecules. The study also explores the reaction mechanisms and the selectivity of the reactions, providing insights into the intermediates involved in the allylation process. The new reagents demonstrated remarkable reactivity, stability, and atom economy, addressing some of the drawbacks of conventional allylation methods such as poor stability, toxicity, and high cost.
10.1007/BF00512971
The research focuses on the synthesis of acylated derivatives of (2'-hydroxyethyl)amino- and (2'-aminoethyl)amino-1,3,5-triazines, which are compounds of interest due to their potential use as herbicides. The purpose of the study is to improve the selectivity and detoxication rate of these herbicides in soil and plants by introducing labile functional groups into the triazine molecule. The researchers used chloroacetyl chloride as an acylating agent to react with (2'-hydroxyethyl)aminotriazines, resulting in (2'-chloroacetoxyethyl)aminotriazines, which were then further reacted with potassium thiocyanate to obtain (2'-thiocyanoacetoxyethyl)aminotriazines. Additionally, they synthesized monoacylethylenediamines and reacted them with chlorotriazines to produce (2'-acylaminoethyl)amino-1,3,5-triazines. The study concluded that the introduction of these functional groups indeed resulted in compounds with enhanced selectivity and faster detoxication, addressing some of the disadvantages associated with traditional triazine herbicides.
10.1039/c4cc00805g
The research aims to develop solvatochromic dyes capable of detecting hydrogen-bond-donating solvents, such as water, independent of polarity. The purpose is to overcome the challenge of monitoring hydrogen bonding interactions separately from polarity, as both factors influence molecular conformations, reaction rates, and chemical equilibria. The researchers synthesized two organic dyes, 6-(3-aminophenyl)-1,3,5-triazine-2,4-diamine (MADAT) and its acetylated analog, AMADAT, which exhibit unique solvatochromism due to the triazine architecture. These dyes show significant bathochromic shifts in their emission spectra when exposed to protic solvents, indicating their potential to monitor hydrogen-bonding interactions. The study concludes that these new solvatochromic dyes can be used to monitor hydrogen-bonding interactions without the influence of environmental polarity, and that the triazine architecture can be a basis for developing a range of new solvatochromic materials for detecting hydrogen-bond-donating species.
