(2R,3S)-2-Methyl-5-oxo-4-(phenylMethyl)-3-Morpholinecarboxylic acid

Base Information

Chemical Name:(2R,3S)-2-Methyl-5-oxo-4-(phenylMethyl)-3-Morpholinecarboxylic acid
CAS No.:681851-25-2
Molecular Formula:C13H15NO4
Molecular Weight:249.266
Hs Code.:
Mol file:681851-25-2.mol

Synonyms:(2R,3S)-2-Methyl-5-oxo-4-(phenylmethyl)-3-morpholinecarboxylic acid;(2R,3S)-4-benzyl-2-methyl-5-oxomorpholine-3-carboxylic acid;(2R,3S)-4-Benzyl-2-methyl-5-oxo-morpholine-3-carboxylic acid;(3S)-4-benzyl-2-methyl-5-oxomorpholine-3-carboxylic acid;

Suppliers and Price of (2R,3S)-2-Methyl-5-oxo-4-(phenylMethyl)-3-Morpholinecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (2R,3S)-2-Methyl-5-oxo-4-(phenylMethyl)-3-Morpholinecarboxylic acid

Chemical Property:

PSA：66.84000
LogP:0.82500

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2R,3S)-2-Methyl-5-oxo-4-(phenylMethyl)-3-Morpholinecarboxylic acid

There total 2 articles about (2R,3S)-2-Methyl-5-oxo-4-(phenylMethyl)-3-Morpholinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 94625-13-5
(2S,3R)-2-(benzylamino)-3-hydroxybutanoic acid

: 79-04-9
chloroacetyl chloride

: 681851-25-2
(2R,3S)-2-methyl-5-oxo-4-(phenylmethyl)morpholine-3-carboxylic acid

Guidance literature:: (2S,3R)-2-(benzylamino)-3-hydroxybutanoic acid; chloroacetyl chloride; With potassium carbonate; In tetrahydrofuran; water; at 0 ℃;

With sodium hydroxide; In tetrahydrofuran; water; at 5 ℃; for 4h;

Reference yield:

: 100-52-7
benzaldehyde

: 681851-25-2
(2R,3S)-2-methyl-5-oxo-4-(phenylmethyl)morpholine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water / 1 h / 25 °C

1.2: 12 h / 0 - 25 °C

2.1: potassium carbonate / tetrahydrofuran; water / 0 °C

2.2: 4 h / 5 °C

With potassium carbonate; sodium hydroxide; In tetrahydrofuran; water;