Ethanedione, bis[4-(diethylamino)phenyl]-

Base Information

• Chemical Name: Ethanedione, bis[4-(diethylamino)phenyl]-
• CAS No.: 68289-19-0
• Molecular Formula: C22H28N2O2
• Molecular Weight: 352.477
• DSSTox Substance ID: DTXSID00404928
• Nikkaji Number: J1.769.463D
• Wikidata: Q82209280
• Mol file: 68289-19-0.mol

Synonyms:Ethanedione, bis[4-(diethylamino)phenyl]-;68289-19-0;1,2-bis(4-diethylaminophenyl)ethane-1,2-dione;SCHEMBL1306139;DTXSID00404928;GHFPJMPRTWGOTF-UHFFFAOYSA-N;AKOS002377220;1,2-bis(4-diethylaminophenyl)-ethane-1,2-dione;1,2-Bis[4-(diethylamino)phenyl]-1,2-ethanedione

Chemical Property of Ethanedione, bis[4-(diethylamino)phenyl]-

Chemical Property:

• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 352.215078140
• Heavy Atom Count: 26
• Complexity: 399

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C1=CC=C(C=C1)C(=O)C(=O)C2=CC=C(C=C2)N(CC)CC

Technology Process of Ethanedione, bis[4-(diethylamino)phenyl]-

There total 5 articles about Ethanedione, bis[4-(diethylamino)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

oxalyl dichloride (79-37-8) + N,N-diethylaniline (91-66-7) → 1,2-bis(4-(diethylamino)phenyl)ethane-1,2-dione (68289-19-0)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at 5 ℃; for 4h;

Reference yield: 65.0%

1H-1,2,3-benzotriazol-1-yl(4-diethylaminophenyl)-1,2-ethanedione (306990-96-5) → 1,2,3-Benzotriazole (95-14-7,27556-51-0) + 1,2-bis(4-(diethylamino)phenyl)ethane-1,2-dione (68289-19-0)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; at 20 ℃; for 0.0833333h;

DOI:10.1016/S0040-4020(03)00575-1

Reference yield: 65.0%

1H-1,2,3-benzotriazol-1-yl(4-diethylaminophenyl)-1,2-ethanedione (306990-96-5) → 1,2-bis(4-(diethylamino)phenyl)ethane-1,2-dione (68289-19-0)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; at 20 ℃; for 0.0833333h;

DOI:10.1016/S0040-4039(02)01080-8

upstream raw materials:

oxalyl dichloride

N,N-diethylaniline

1,2-bis(4-fluorophenyl)ethane-1,2-dione

diethylamine

Downstream raw materials:

1,2-Bis<4,4'-N,N-diethylamino-phenyl>-1-hydroxy-ethan-2-on