3-(4-BENZYLOXYPHENYL)PROPIONALDEHYDE

Base Information

• Chemical Name: 3-(4-BENZYLOXYPHENYL)PROPIONALDEHYDE
• CAS No.: 68486-77-1
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• Hs Code.: 2912499000
• Mol file: 68486-77-1.mol

Synonyms:Propanal,3-(4-benzyloxyphenyl);Benzenepropanal,4-(phenylmethoxy);3-[4-(Benzyloxy)phenyl]propanal;

Chemical Property of 3-(4-BENZYLOXYPHENYL)PROPIONALDEHYDE

Chemical Property:

• Vapor Pressure: 8.49E-06mmHg at 25°C
• PSA: 26.30000
• LogP: 3.39710

Purity/Quality:

98% ^*data from raw suppliers

3-(4-(Benzyloxy)phenyl)propanal 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(4-BENZYLOXYPHENYL)PROPIONALDEHYDE

There total 32 articles about 3-(4-BENZYLOXYPHENYL)PROPIONALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-[4-(benzyloxy)phenyl]propan-1-ol (61440-45-7) → 3-(4-(benzyloxy)phenyl)propanal (68486-77-1)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tetlet.2004.07.025

Reference yield: 92.0%

4-benzyloxycinnamaldehyde (84184-53-2) → 3-(4-(benzyloxy)phenyl)propanal (68486-77-1)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; dibenzylammonium trifluoroacetate salt; In tetrahydrofuran; at 20 ℃; for 5h;

DOI:10.1002/anie.200461816

Reference yield: 92.0%

ethyl 3-(4-(benzyloxy)phenyl)propanoate (186895-45-4) → 3-(4-(benzyloxy)phenyl)propanal (68486-77-1)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; toluene; at -70 ℃; Inert atmosphere;

DOI:10.1002/hlca.201500073

upstream raw materials:

3-[4-(benzyloxy)phenyl]propan-1-ol

2-(2-p-benzyloxyphenylethyl)-4,4,6-trimethylperhydro-1,3-oxazine

3-(4-benzyloxyphenyl)-N-methoxy-N-methyl-propionamide

3-(4-benzyloxyphenyl)propanoic acid

Downstream raw materials:

2-(2-p-benzyloxyphenylethyl)-1,3-dithian

6-[2-(4-benzyloxy-phenyl)-ethyl]-4-hydroxy-5,6-dihydro-pyran-2-one

(E)-5-(4-Benzyloxy-phenyl)-pent-2-enoic acid methyl ester

(R)-4-benzyloxy-6-(4-benzyloxyphenyl)hex-1-ene

Refernces

• 1、 Pandey, Ganesh,Laha, Ramkrishna,Mondal, Pradip Kumar. "Heterocyclization involving benzylic C(sp3)-H functionalization enabled by visible light photoredox catalysis". . p. 9689 - 9692. Retrieved 2019/08/15.
• 2、 Zhou, Qingqing,Reekie, Tristan A.,Abbassi, Ramzi H.,Venkata, Dinesh Indurthi,Font, Josep S.,Ryan, Renae M.,Rendina, Louis M.,Munoz, Lenka,Kassiou, Michael. "Flexible Analogues of Azaindole DYRK1A Inhibitors Elicit Cytotoxicity in Glioblastoma Cells". . p. 789 - 797. Retrieved 2018/09/11.