4-(3-Methyl-1H-indol-2-yl)phenol

Base Information

Chemical Name:4-(3-Methyl-1H-indol-2-yl)phenol
CAS No.:69181-53-9
Molecular Formula:C15H13NO
Molecular Weight:223.274
Hs Code.:
ChEMBL ID:CHEMBL4636920
DSSTox Substance ID:DTXSID00499435
Wikidata:Q82350208

Synonyms:4-(3-Methyl-1H-indol-2-yl)phenol;69181-53-9;SCHEMBL9775886;CHEMBL4636920;DTXSID00499435

Suppliers and Price of 4-(3-Methyl-1H-indol-2-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(3-Methyl-1H-indol-2-yl)phenol

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:223.099714038
Heavy Atom Count:17
Complexity:260

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(NC2=CC=CC=C12)C3=CC=C(C=C3)O

Technology Process of 4-(3-Methyl-1H-indol-2-yl)phenol

There total 6 articles about 4-(3-Methyl-1H-indol-2-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 198479-60-6
2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

: 69181-53-9
4-(3-methyl-1H-indol-2-yl)phenol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; ethanol; at 20 ℃; for 18h;
DOI:10.1021/acsmedchemlett.9b00557

Reference yield: 90.0%

: 100-63-0
phenylhydrazine

: 70-70-2
4-hydroxypropiophenone

: 69181-53-9
4-(3-methyl-1H-indol-2-yl)phenol

Guidance literature:: With acetic acid; zinc(II) chloride; at 20 - 90 ℃; for 6h; Inert atmosphere;

Reference yield:

: 4495-66-3
4-benzyloxypropiophenone

: 69181-53-9
4-(3-methyl-1H-indol-2-yl)phenol

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / methanol / 24 h / Reflux

2: palladium 10% on activated carbon; hydrogen / ethanol; tetrahydrofuran / 18 h / 20 °C

With sulfuric acid; palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; methanol; ethanol; 1: |Fischer Indole Synthesis;
DOI:10.1021/acsmedchemlett.9b00557