4-Bromo-3-isopropyl-1H-indazole

Base Information

Chemical Name:4-Bromo-3-isopropyl-1H-indazole
CAS No.:693285-71-1
Molecular Formula:C10H11BrN2
Molecular Weight:239.11200
Hs Code.:
DSSTox Substance ID:DTXSID80699239
Wikidata:Q82630079
Mol file:693285-71-1.mol

Synonyms:4-BROMO-3-ISOPROPYL-1H-INDAZOLE;693285-71-1;4-bromo-3-propan-2-yl-2H-indazole;4-Bromo-3-(propan-2-yl)-1H-indazole;SCHEMBL61904;DTXSID80699239;XEXVOZFTCDGRDR-UHFFFAOYSA-N;4-Bromo-3-(propan-2-yl)-2H-indazole;CS-0056170;F73460

Suppliers and Price of 4-Bromo-3-isopropyl-1H-indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
4-Bromo-3-isopropyl-1H-indazole 95+%
250mg
$ 722.00

American Custom Chemicals Corporation
4-BROMO-3-(1-METHYLETHYL)-1H-INDAZOLE 95.00%
5MG
$ 501.59

Total 7 raw suppliers

Chemical Property of 4-Bromo-3-isopropyl-1H-indazole

Chemical Property:

PSA：28.68000
LogP:3.44880
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:238.01056
Heavy Atom Count:13
Complexity:184

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-3-isopropyl-1H-indazole 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=C2C(=NN1)C=CC=C2Br

Technology Process of 4-Bromo-3-isopropyl-1H-indazole

There total 5 articles about 4-Bromo-3-isopropyl-1H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 693285-70-0
1-(2-bromo-6-fluoro-phenyl)-2-methyl-propan-1-one

: 693285-71-1
4-bromo-3-isopropyl-1H-indazole

Guidance literature:: With hydrazine; In 2-ethoxy-ethanol; at 160 ℃; for 16h; Heating / reflux;

Reference yield:

: 1073-06-9
3-fluorobromobenzene

: 97-72-3
2-Methylpropionic anhydride

: 693285-71-1
4-bromo-3-isopropyl-1H-indazole

Guidance literature:: 3-fluorobromobenzene; With n-butyllithium; diisopropylamine; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

2-Methylpropionic anhydride; In tetrahydrofuran; for 0.25h; Inert atmosphere;

With hydrazine hydrate; In ethylene glycol; at 0 - 100 ℃;

Reference yield:

: 1073-06-9
3-fluorobromobenzene

: 693285-71-1
4-bromo-3-isopropyl-1H-indazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: 2,2,6,6-tetramethyl-piperidine; n-butyllithium / tetrahydrofuran; hexane / 3.33 h / -78 °C

1.2: 1 h / -78 - 20 °C

2.1: tetrahydrofuran; diethyl ether / 1 h / -78 - 0 °C

3.1: hydrazine / ethylene glycol / 16 h / 160 °C

With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; hydrazine; In tetrahydrofuran; diethyl ether; hexane; ethylene glycol;