Benzene, 1-methoxy-3-(1,2-propadienyl)-

Base Information

• Chemical Name: Benzene, 1-methoxy-3-(1,2-propadienyl)-
• CAS No.: 70090-80-1
• Molecular Formula: C10H10O
• Molecular Weight: 146.189
• DSSTox Substance ID: DTXSID60458624
• Nikkaji Number: J1.825.393C
• Mol file: 70090-80-1.mol

Synonyms:Benzene, 1-methoxy-3-(1,2-propadienyl)-;3-Methoxyphenylallene;70090-80-1;DTXSID60458624

Chemical Property of Benzene, 1-methoxy-3-(1,2-propadienyl)-

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 146.073164938
• Heavy Atom Count: 11
• Complexity: 156

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)C=C=C

Technology Process of Benzene, 1-methoxy-3-(1,2-propadienyl)-

There total 5 articles about Benzene, 1-methoxy-3-(1,2-propadienyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-methoxy-1-iodobenzene (766-85-8) + allenyltributylstannane (53915-69-8) → 1-methoxy-3-(propa-1,2-dien-1-yl)benzene (70090-80-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride; In N,N-dimethyl-formamide; at 50 ℃; for 24h;

DOI:10.1016/S0040-4020(03)00516-7

Reference yield: 77.0%

1-(2,2-dibromocyclopropyl)-3-methoxybenzene (65038-17-7) → 1-methoxy-3-(propa-1,2-dien-1-yl)benzene (70090-80-1)

Guidance literature:

With ethylmagnesium bromide; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere; Cooling with ice;

DOI:10.1002/chem.201805097

Reference yield: 72.0%

(3-methoxyphenyl)magnesium bromide (36282-40-3) + propargyl bromide (106-96-7) → m-anisylacetylene (53799-94-3) + 1-methoxy-3-(propa-1,2-dien-1-yl)benzene (70090-80-1)

Guidance literature:

With bis(acetylacetonate)nickel(II); triphenylphosphine; In tetrahydrofuran; at 20 ℃; regioselective reaction; Inert atmosphere;

DOI:10.1055/s-0031-1290365

upstream raw materials:

3-methoxyphenyl methanesulfonate

allenyltributylstannane

3-methoxy-1-iodobenzene

(3-methoxyphenyl)magnesium bromide