3-(Benzyloxy)-4-bromophenol

Base Information

• Chemical Name: 3-(Benzyloxy)-4-bromophenol
• CAS No.: 70120-18-2
• Molecular Formula: C13H11BrO2
• Molecular Weight: 279.133
• DSSTox Substance ID: DTXSID20576651
• Wikidata: Q82466471

Synonyms:3-(benzyloxy)-4-bromophenol;70120-18-2;4-bromo-3-phenylmethoxyphenol;3-benzyloxy-4-bromophenol;Phenol, 4-bromo-3-(phenylmethoxy)-;SCHEMBL5951406;DTXSID20576651;DNSGVSFZTCXNCE-UHFFFAOYSA-N;AKOS037652073

Chemical Property of 3-(Benzyloxy)-4-bromophenol

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 277.99424
• Heavy Atom Count: 16
• Complexity: 204

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=C(C=CC(=C2)O)Br

Technology Process of 3-(Benzyloxy)-4-bromophenol

There total 9 articles about 3-(Benzyloxy)-4-bromophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-benzyloxy-4-(p-toluenesulfonyloxy)bromobenzene (936711-99-8) → 3-(benzyloxy)-4-bromophenol (70120-18-2)

Guidance literature:

2-benzyloxy-4-(p-toluenesulfonyloxy)bromobenzene; With sodium hydroxide; In methanol; for 12h; Inert atmosphere; Reflux;

With hydrogenchloride; In water; pH=1;

DOI:10.1246/bcsj.20110309

Reference yield: 55.0%

4-Bromoresorcinol (6626-15-9) + benzyl bromide (100-39-0) → 2,4-dibenzyloxybromobenzene (55583-11-4) + 3-(benzyloxy)-4-bromophenol (70120-18-2)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2014.01.142

Reference yield: 31.0%

4-Bromoresorcinol (6626-15-9) + benzyl bromide (100-39-0) → 3-(benzyloxy)-4-bromophenol (70120-18-2)

Guidance literature:

With sodium hydrogencarbonate; In acetonitrile; at 80 ℃; Inert atmosphere;

DOI:10.1039/c6md00377j

upstream raw materials:

2-benzyloxy-4-(p-toluenesulfonyloxy)bromobenzene

4-Bromoresorcinol

4-bromo-3-hydroxy-phenyl 4-methyl-benzenesulfonate

benzyl bromide

Downstream raw materials:

2,2'-bis(benzyloxy)-4,4'-dimethoxybiphenyl

2,2'-dihydroxy-4,4'-dimethoxybiphenyl

C₃₈H₃₂O₄P₂

C₃₈H₃₂O₂P₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 70120-18-2 Phenol, 4-bromo-3-(phenylmethoxy)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send