(2S)-2-[(azaniumylacetyl)amino]-4-(methylsulfanyl)butanoate

Base Information

• Chemical Name: (2S)-2-[(azaniumylacetyl)amino]-4-(methylsulfanyl)butanoate
• CAS No.: 554-94-9
• Molecular Formula: C7H14 N2 O3 S
• Molecular Weight: 206.266
• Hs Code.: 2930909090
• Mol file: 554-94-9.mol

Synonyms:GLY-MET;GM zwitterion;Gly-Met zwitterion;Gly-L-Met zwitterion;glycylmethionine zwitterion;glycyl-L-methionine zwitterion;CHEBI:74393;(2S)-2-[(azaniumylacetyl)amino]-4-(methylsulfanyl)butanoate

Chemical Property of (2S)-2-[(azaniumylacetyl)amino]-4-(methylsulfanyl)butanoate

Chemical Property:

• Melting Point: 140-145 °C
• Boiling Point: 493.7±45.0 °C(Predicted)
• PKA: 3.06±0.10(Predicted)
• PSA: 117.72000
• Density: 1.267±0.06 g/cm3(Predicted)
• LogP: 0.35880
• Storage Temp.: −20°C
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 206.07251349
• Heavy Atom Count: 13
• Complexity: 181

Purity/Quality:

99% ^*data from raw suppliers

Gly-Met-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CSCCC(C(=O)[O-])NC(=O)C[NH3+]
• Isomeric SMILES: CSCC[C@@H](C(=O)[O-])NC(=O)C[NH3+]

Technology Process of (2S)-2-[(azaniumylacetyl)amino]-4-(methylsulfanyl)butanoate

There total 8 articles about (2S)-2-[(azaniumylacetyl)amino]-4-(methylsulfanyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-seryl-L-methionine (3227-09-6,117426-06-9) → formaldehyd (50-00-0,30525-89-4,61233-19-0) + Gly-Met (554-94-9)

Guidance literature:

With water; dinitrogen monoxide; Mechanism; Irradiation; other peptides; other reaction partners;

DOI:10.1021/ja00090a012

Reference yield:

N-chloroacetyl-L-methionine (57230-01-0) → Gly-Met (554-94-9)

Guidance literature:

With ammonia; water; at 70 ℃;

Reference yield:

N-(N-benzyloxycarbonyl-glycyl)-L-methionine (3561-48-6) → Gly-Met (554-94-9)

Guidance literature:

With ammonia; sodium; dann Einwirkung von Methyljodid;

upstream raw materials:

N-chloroacetyl-L-methionine

N-(N-benzyloxycarbonyl-glycyl)-L-methionine

L-methionine

glycine

Downstream raw materials:

carbon dioxide

4-carboxybenzophenone radical

benzophenone-4-carboxylic acid radical anion

L-methionine

Refernces

• 1、 Sch?neich, Christian,Zhao, Fang,Madden, Keith P.,Bobrowski, Krzysztof. "Side chain fragmentation of N-terminal threonine or serine residue induced through intramolecular proton transfer to hydroxy sulfuranyl radical formed at neighboring methionine in dipeptides". . p. 4641 - 4652. Retrieved 2007/10/02.