2,2-Dimethyl-3-phenyl-2H-1,4-benzoxazine

Base Information

Chemical Name:2,2-Dimethyl-3-phenyl-2H-1,4-benzoxazine
CAS No.:70310-25-7
Molecular Formula:C16H15NO
Molecular Weight:237.301
Hs Code.:
DSSTox Substance ID:DTXSID40499651
Wikidata:Q82350630

Synonyms:70310-25-7;2,2-Dimethyl-3-phenyl-2H-1,4-benzoxazine;DTXSID40499651

Suppliers and Price of 2,2-Dimethyl-3-phenyl-2H-1,4-benzoxazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2,2-Dimethyl-3-phenyl-2H-1,4-benzoxazine

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:237.115364102
Heavy Atom Count:18
Complexity:328

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(=NC2=CC=CC=C2O1)C3=CC=CC=C3)C

Technology Process of 2,2-Dimethyl-3-phenyl-2H-1,4-benzoxazine

There total 5 articles about 2,2-Dimethyl-3-phenyl-2H-1,4-benzoxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.0%

: 10409-54-8
2-bromo-2-methyl-1-phenyl-propan-1-one

: 95-55-6
2-amino-phenol

: 70310-25-7
2,2-dimethyl-3-phenyl-2H-1,4-benzoxazine

Guidance literature:: 2-bromo-2-methyl-1-phenyl-propan-1-one; 2-amino-phenol; With potassium carbonate; In acetone; at 20 ℃; for 3h;

With potassium carbonate; In acetone; for 6h; Reflux;
DOI:10.1021/acs.joc.8b02867

Reference yield:

: 70310-20-2
2-methyl-2-(2-nitro-phenoxy)-1-phenyl-propan-1-one

: 70310-25-7
2,2-dimethyl-3-phenyl-2H-1,4-benzoxazine

Guidance literature:: With sodium hypophosphite; palladium on activated charcoal; In tetrahydrofuran; water;
DOI:10.1055/s-1979-28629

Reference yield:

: 611-70-1
phenyl isopropyl ketone

: 70310-25-7
2,2-dimethyl-3-phenyl-2H-1,4-benzoxazine

Guidance literature:: Multi-step reaction with 2 steps

1.1: aluminum (III) chloride; bromine / diethyl ether

2.1: potassium carbonate / acetone / 3 h / 20 °C

2.2: 6 h / Reflux

With aluminum (III) chloride; bromine; potassium carbonate; In diethyl ether; acetone;
DOI:10.1021/acs.joc.8b02867