1,3-Bis[3-(trifluoromethyl)phenyl]propan-2-one

Base Information

Chemical Name:1,3-Bis[3-(trifluoromethyl)phenyl]propan-2-one
CAS No.:71792-93-3
Molecular Formula:C17H12F6O
Molecular Weight:346.272
Hs Code.:
DSSTox Substance ID:DTXSID70529470
Nikkaji Number:J2.629.744C
Wikidata:Q82399909

Synonyms:1,3-Bis[3-(trifluoromethyl)phenyl]propan-2-one;71792-93-3;SCHEMBL6865758;DTXSID70529470;PVWRQYUVLKSIMF-UHFFFAOYSA-N

Suppliers and Price of 1,3-Bis[3-(trifluoromethyl)phenyl]propan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1,3-Bis[3-(trifluoromethyl)phenyl]propan-2-one

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:346.07923397
Heavy Atom Count:24
Complexity:390

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(F)(F)F)CC(=O)CC2=CC(=CC=C2)C(F)(F)F

Technology Process of 1,3-Bis[3-(trifluoromethyl)phenyl]propan-2-one

There total 3 articles about 1,3-Bis[3-(trifluoromethyl)phenyl]propan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 62451-84-7
(3-trifluoromethyl-phenyl)-acetic acid methyl ester

: 71792-93-3
1,3-bis(3-(trifluoromethyl)phenyl)propan-2-one

Guidance literature:: With lithium diisopropyl amide; In diethyl ether; hexane; at 0 - 20 ℃;
DOI:10.1016/j.tet.2008.05.030

Reference yield: 53.0%

: 541-41-3
chloroformic acid ethyl ester

: 705-29-3
3-Trifluoromethylbenzyl chloride

: 71792-93-3
1,3-bis(3-(trifluoromethyl)phenyl)propan-2-one

Guidance literature:: With [2,2]bipyridinyl; chloro-trimethyl-silane; nickel(II) bromide 2-methoxyethyl ether complex; zinc; In tetrahydrofuran; N,N-dimethyl acetamide; at 40 ℃; for 2h; Sealed tube; Inert atmosphere;
DOI:10.1002/anie.201903330