2,2'-Bibenzoxazole

Base Information

• Chemical Name: 2,2'-Bibenzoxazole
• CAS No.: 7210-07-3
• Molecular Formula: C14H8N2O2
• Molecular Weight: 236.23
• Mol file: 7210-07-3.mol

Synonyms:

Chemical Property of 2,2'-Bibenzoxazole

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2'-Bibenzoxazole

There total 4 articles about 2,2'-Bibenzoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

benzoxazole (273-53-0,29791-96-6) + ortho-nitrobenzoic acid (552-16-9,104810-18-6) → 1-nitro-2-(2-nitrophenyl)benzene (2436-96-6) + 2,2'-bibenzo[d]oxazole (7210-07-3) + 2-(2′-nitrophenyl)-1,3-benzoxazole (840-37-9)

Guidance literature:

With 1,10-Phenanthroline; caesium carbonate; silver carbonate; copper(l) chloride; In N,N-dimethyl-formamide; at 110 ℃; for 23h; Reagent/catalyst; Inert atmosphere;

DOI:10.1039/c5cc06645j

Reference yield: 45.0%

1-methyl-1H-imidazole (616-47-7) + benzoxazole (273-53-0,29791-96-6) → 1,1'-dimethyl-2,2'-biimidazole (37570-94-8) + 2-(1-methyl-1H-imidazole-2-yl)benzo[d]oxazole (1207558-62-0) + 2,2'-bibenzo[d]oxazole (7210-07-3)

Guidance literature:

With copper diacetate; In 5,5-dimethyl-1,3-cyclohexadiene; at 140 ℃; for 12h; regioselective reaction;

DOI:10.1039/b919396k

Reference yield: 39.0%

benzoxazole (273-53-0,29791-96-6) + ortho-nitrobenzoic acid (552-16-9,104810-18-6) → 1-nitro-2-(2-nitrophenyl)benzene (2436-96-6) + 2,2'-bibenzo[d]oxazole (7210-07-3) + nitrobenzene (98-95-3,26969-40-4) + 2-(2′-nitrophenyl)-1,3-benzoxazole (840-37-9)

Guidance literature:

With 1,10-Phenanthroline; potassium tert-butylate; copper(l) chloride; silver(l) oxide; In N,N-dimethyl-formamide; at 110 ℃; for 23h; Reagent/catalyst; Inert atmosphere;

DOI:10.1039/c5cc06645j

upstream raw materials:

1-methyl-1H-imidazole

benzoxazole

ortho-nitrobenzoic acid

Refernces

• 1、 Li, Yan,Jin, Jun,Qian, Weixing,Bao, Weiliang. "An efficient and convenient Cu(OAc)2/air mediated oxidative coupling of azoles via C-H activation". supporting information; experimental part. p. 326 - 330. Retrieved 2010/02/16.