2-Amino-4-phenyl-3-furonitrile

Base Information

Chemical Name:2-Amino-4-phenyl-3-furonitrile
CAS No.:72982-21-9
Molecular Formula:C11H8N2O
Molecular Weight:184.197
Hs Code.:
DSSTox Substance ID:DTXSID60472800
Nikkaji Number:J1.649.272H
Wikidata:Q82301948

Synonyms:2-amino-4-phenylfuran-3-carbonitrile;72982-21-9;2-amino-4-phenyl-3-furonitrile;3-Furancarbonitrile, 2-amino-4-phenyl-;2-amino-4-phenyl-furan-3-carbonitrile;SCHEMBL1785236;DTXSID60472800;QNGBQONBZBPFQI-UHFFFAOYSA-N;AKOS022264784;AT13858;CS-0223744;EN300-1165318

Suppliers and Price of 2-Amino-4-phenyl-3-furonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Amino-4-phenyl-3-furonitrile

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:184.063662883
Heavy Atom Count:14
Complexity:239

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=COC(=C2C#N)N

Technology Process of 2-Amino-4-phenyl-3-furonitrile

There total 6 articles about 2-Amino-4-phenyl-3-furonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 582-24-1
1-phenyl-2-hydroxyethanone

: 109-77-3
malononitrile

: 72982-21-9
2-amino-4-phenylfuran-3-carbonitrile

Guidance literature:: With diethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1021/acs.jmedchem.6b00608

Reference yield: 40.0%

: 59790-95-3
2-amino-4,5-dihydro-4-phenyl-3-furancarbonitrile

: 72982-21-9
2-amino-4-phenylfuran-3-carbonitrile

Guidance literature:: With 50% palladium on charcoal; In 5,5-dimethyl-1,3-cyclohexadiene; at 150 ℃; for 5h; Inert atmosphere;
DOI:10.1039/c9cc08781h

Reference yield:

: 100-52-7
benzaldehyde

: 72982-21-9
2-amino-4-phenylfuran-3-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 44 percent / N-ethylbenzothiazolium bromide; Et₃N / Heating

2: 39 percent / Et₃N / methanol / 15 h / 20 °C

With triethylamine; 3-ethylbenzothiazolium bromide; In methanol;
DOI:10.1002/jhet.5570380526