Phosphoric acid, cyclohexyl dimethyl ester

Base Information

• Chemical Name: Phosphoric acid, cyclohexyl dimethyl ester
• CAS No.: 7301-84-0
• Molecular Formula: C8H17O4P
• Molecular Weight: 208.194
• Mol file: 7301-84-0.mol

Synonyms:

Chemical Property of Phosphoric acid, cyclohexyl dimethyl ester

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phosphoric acid, cyclohexyl dimethyl ester

There total 6 articles about Phosphoric acid, cyclohexyl dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

cyclohexanol (108-93-0) + phosphorous acid trimethyl ester (121-45-9) → Phosphoric acid cyclohexyl dimethyl ester (7301-84-0)

Guidance literature:

With pyridine; carbon tetrabromide; for 2.75h; Ambient temperature;

DOI:10.1021/jo00117a018

Reference yield: 38.0%

Dimethyl chlorophosphate (813-77-4) + cyclohexanol (108-93-0) → Phosphoric acid cyclohexyl dimethyl ester (7301-84-0)

Guidance literature:

With titanium(IV) tetrabutoxide; triethylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/jo034331g

Reference yield:

cyclohexane (110-82-7,25012-93-5) + phosphorous acid trimethyl ester (121-45-9) → Phosphoric acid cyclohexyl dimethyl ester (7301-84-0) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + cyclohexanol (108-93-0)

Guidance literature:

With oxygen; iron(III) chloride; zinc; Yield given. Multistep reaction. Yields of byproduct given; 1) pyridine, acetic acid, 0 deg C, 2 h 2) r.t., 5 h;

DOI:10.1016/S0040-4039(00)92278-0

upstream raw materials:

cyclohexanol

sodium cyclohexanolate

Dimethyl chlorophosphate

N,N-dimethyl-O,O-dimethylphosphoramidate

Refernces

• 1、 Oza, Vibha B.,Corcoran, Robert C.. "A Mild Preparation of Protected Phosphate Esters from Alcohols". . p. 3680 - 3684. Retrieved 2007/10/02.