8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester

Base Information

Chemical Name:8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester
CAS No.:73045-45-1
Molecular Formula:C11H17NO2
Molecular Weight:195.25800
Hs Code.:
Mol file:73045-45-1.mol

Synonyms:(1R,5S)-anhydroecgonin ethyl ester;(1R)-Trop-2-en-2-carbonsaeure-aethylester;8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester;anhydroecgonin ethyl ester;(1R)-trop-2-ene-2-carboxylic acid ethyl ester;R-anhydroecgonine ethyl ester;

Suppliers and Price of 8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester
25mg
$ 460.00

TRC
EcgonidineEthylEster
25mg
$ 185.00

American Custom Chemicals Corporation
8-AZABICYCLO[3.2.1]OCT-2-ENE-2-CARBOXYLIC ACID-8-METHYL-ETHYL ESTER 95.00%
5MG
$ 497.33

Total 0 raw suppliers

Chemical Property of 8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester

Chemical Property:

PSA：29.54000
LogP:1.28030

Purity/Quality:: 8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester is a chemical intermediate derived from ecgonine (E325550) and the combustion metabolite of cocaine.

Technology Process of 8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester

There total 6 articles about 8-Azabicyclo[3.2.1]oct-2-ene-2-carboxylic Acid 8-Methyl-Ethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 64-17-5
ethanol

: (-)-ecgonidine ; hydrobromide

: 73045-45-1
anhydroecgonine ethyl ester

Guidance literature:: ethanol; (-)-ecgonidine ; hydrobromide; With sulfuric acid; for 2h; Reflux;

With sodium carbonate; In water; at 20 - 25 ℃;

Reference yield:

: 64-17-5
ethanol

: 141-52-6
sodium ethanolate

: ecgonine methylester

: 73045-45-1
anhydroecgonine ethyl ester

Guidance literature:: ethanol; sodium ethanolate; ecgonine methylester; In ethyl acetate; at 18 - 65 ℃; for 2h; Industry scale;

With acetic acid; In ethyl acetate; at 18 - 58 ℃; vacuum;

With sodium hydroxide; In water; toluene; at 24 ℃; pH=8.5;

Reference yield:

: 64-17-5
ethanol

: 50-36-2
Cocaine

: 73045-45-1
anhydroecgonine ethyl ester

Guidance literature:: Cocaine; With hydrogenchloride; In water; at 100 ℃; for 21h;

With trichlorophosphate; at 100 ℃; for 20h;

ethanol; for 67h;
DOI:10.1021/tx0255828