N-[1-(2-Phenylethyl)piperidin-4-yl]-1H-benzimidazol-2-amine

Base Information

Chemical Name:N-[1-(2-Phenylethyl)piperidin-4-yl]-1H-benzimidazol-2-amine
CAS No.:73734-45-9
Molecular Formula:C20H24N4
Molecular Weight:320.437
Hs Code.:
ChEMBL ID:CHEMBL60746
DSSTox Substance ID:DTXSID90512420
Wikidata:Q82371639

Synonyms:73734-45-9;N-[1-(2-Phenylethyl)piperidin-4-yl]-1H-benzimidazol-2-amine;CHEMBL60746;SCHEMBL11266594;DTXSID90512420;RJLNAXGKPVBEDW-UHFFFAOYSA-N;N-[1-(2-phenylethyl)-4-piperidinyl]-1H-benzimidazol-2-amine

Suppliers and Price of N-[1-(2-Phenylethyl)piperidin-4-yl]-1H-benzimidazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of N-[1-(2-Phenylethyl)piperidin-4-yl]-1H-benzimidazol-2-amine

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:320.20009678
Heavy Atom Count:24
Complexity:374

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1NC2=NC3=CC=CC=C3N2)CCC4=CC=CC=C4

Technology Process of N-[1-(2-Phenylethyl)piperidin-4-yl]-1H-benzimidazol-2-amine

There total 6 articles about N-[1-(2-Phenylethyl)piperidin-4-yl]-1H-benzimidazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.6%

: 103-63-9
1-phenyl-2-bromoethane

: 75970-47-7
(1H-benzimidazol-2-yl)-(4-piperidinyl)amine dihydrobromide

: 73734-45-9
N-[1-(2-phenylethyl)-4-piperidinyl]-1H-benzimidazol-2-amine

Guidance literature:: With sodium carbonate; In N,N-dimethyl-formamide; at 70 ℃;
DOI:10.1021/jm00150a029

Reference yield:

: 39742-60-4
1-(2-phenylethyl)-4-piperidinone

: 73734-45-9
N-[1-(2-phenylethyl)-4-piperidinyl]-1H-benzimidazol-2-amine

Guidance literature:: Multi-step reaction with 4 steps

1: NH₃, H₂ / 10 percent Pd/C / methanol

2: ethanol / 25 °C

3: H₂ / 10 percent Pd/C

4: HgO/S

With ammonia; hydrogen; sulfur; mercury(II) oxide; palladium on activated charcoal; In methanol; ethanol;
DOI:10.1021/jm00150a029

Reference yield:

: 51448-56-7
4-amino-1-(2-phenylethyl)-piperidine

: 73734-45-9
N-[1-(2-phenylethyl)-4-piperidinyl]-1H-benzimidazol-2-amine

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 25 °C

2: H₂ / 10 percent Pd/C

3: HgO/S

With hydrogen; sulfur; mercury(II) oxide; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00150a029