n-Boc-alpha-(phenylsulfonyl)-4-methoxybenzylamine

Base Information

Chemical Name:n-Boc-alpha-(phenylsulfonyl)-4-methoxybenzylamine
CAS No.:741259-87-0
Molecular Formula:C19H23NO5S
Molecular Weight:377.461
Hs Code.:
European Community (EC) Number:695-641-1
Nikkaji Number:J2.117.311H
Mol file:741259-87-0.mol

Synonyms:741259-87-0;n-boc-alpha-(phenylsulfonyl)-4-methoxybenzylamine;tert-Butyl ((4-methoxyphenyl)(phenylsulfonyl)methyl)carbamate;SCHEMBL12838215;N-Boc-alpha-(phenylsulfonyl)-4-methoxybenzylamine, 95%;[(4-Methoxyphenyl)(phenylsulfonyl) methyl]carbamic acid tert-butyl ester

Suppliers and Price of n-Boc-alpha-(phenylsulfonyl)-4-methoxybenzylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
N-Boc-α-(phenylsulfonyl)-4-methoxybenzylamine 95%
5g
$ 54.50

AK Scientific
N-Boc-α-(phenylsulfonyl)-4-methoxybenzylamine
5g
$ 135.00

Total 2 raw suppliers

Chemical Property of n-Boc-alpha-(phenylsulfonyl)-4-methoxybenzylamine

Chemical Property:

Melting Point:159-164℃
Boiling Point:574.3±50.0 °C(Predicted)
PKA:9.67±0.46(Predicted)
PSA：90.08000
Density:1.211±0.06 g/cm3(Predicted)
LogP:5.16410
Storage Temp.:2-8°C
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:377.12969401
Heavy Atom Count:26
Complexity:550

Purity/Quality:

99% ^*data from raw suppliers

N-Boc-α-(phenylsulfonyl)-4-methoxybenzylamine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(C1=CC=C(C=C1)OC)S(=O)(=O)C2=CC=CC=C2

Technology Process of n-Boc-alpha-(phenylsulfonyl)-4-methoxybenzylamine

There total 2 articles about n-Boc-alpha-(phenylsulfonyl)-4-methoxybenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 4248-19-5
tert-butyl carbazate

: 873-55-2
sodium benzenesulfonate

: 123-11-5
4-methoxy-benzaldehyde

: 741259-87-0
tert-butyl (4-methoxyphenyl)(phenylsulfonyl)methylcarbamate

Guidance literature:: In methanol; formic acid; water; at 20 ℃; for 72h;
DOI:10.1039/c6cc00603e

Reference yield:

: 4248-19-5
tert-butyl carbazate

: 123-11-5
4-methoxy-benzaldehyde

: 618-41-7
Benzenesulfinic acid

: 741259-87-0
tert-butyl (4-methoxyphenyl)(phenylsulfonyl)methylcarbamate

Guidance literature:: With magnesium sulfate; In tetrahydrofuran; dichloromethane; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1002/ejoc.201100426

Reference yield: 99.0%

: 622-42-4
1-nitro-1-phenylmethane

: 741259-87-0
tert-butyl (4-methoxyphenyl)(phenylsulfonyl)methylcarbamate

: tert-butyl [(1S,2R)-1-(4-methoxyphenyl)-2-nitro-2-phenylethyl]carbamate

Guidance literature:: With C₄₄H₅₇N₄O₃⁽¹⁺⁾*Br^(1-); lithium hydroxide; In chloroform; at -40 ℃; for 12h; enantioselective reaction;
DOI:10.1021/acs.joc.7b00306