Methyl 3-oxo-3-(oxan-4-yl)propanoate

Base Information

Chemical Name:Methyl 3-oxo-3-(oxan-4-yl)propanoate
CAS No.:75338-17-9
Molecular Formula:C₉H₁₄O₄
Molecular Weight:186.208
Hs Code.:
European Community (EC) Number:966-140-8
Mol file:75338-17-9.mol

Synonyms:Methyl 3-oxo-3-(oxan-4-yl)propanoate;75338-17-9;methyl 3-(oxan-4-yl)-3-oxopropanoate;TETRAHYDRO-BETA-OXO-2H-PYRAN-4-PROPANOIC ACID METHYL ESTER;2H-Pyran-4-propanoic acid, tetrahydro-beta-oxo-, methyl ester;SCHEMBL3594828;DJMDVBNUOMSULY-UHFFFAOYSA-N;Methyl3-oxo-3-(oxan-4-yl)propanoate;C78443;methyl 3-(4-tetrahydropyranyl)-3-oxopropanoate;EN300-1840949;2H-Pyran-4-propanoic acid, tetrahydro--oxo-, methyl ester

Suppliers and Price of Methyl 3-oxo-3-(oxan-4-yl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
Methyl3-oxo-3-(oxan-4-yl)propanoate 97%
5g
$ 660.00

Total 5 raw suppliers

Chemical Property of Methyl 3-oxo-3-(oxan-4-yl)propanoate

Chemical Property:

Boiling Point:271.2±30.0 °C(Predicted)
PKA:10.30±0.20(Predicted)
Density:1.126±0.06 g/cm3(Predicted)
XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:186.08920892
Heavy Atom Count:13
Complexity:194

Purity/Quality:

99.90% ^*data from raw suppliers

Methyl3-oxo-3-(oxan-4-yl)propanoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)CC(=O)C1CCOCC1

Technology Process of Methyl 3-oxo-3-(oxan-4-yl)propanoate

There total 6 articles about Methyl 3-oxo-3-(oxan-4-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 137052-08-5
1-(tetrahydro-2H-pyran-4-yl)ethan-1-one

: 616-38-6
carbonic acid dimethyl ester

: 75338-17-9
3-oxo-3-(tetrahydropyran-4-yl)propionic acid methyl ester

Guidance literature:: With sodium hydride; In 1,4-dioxane; mineral oil; for 3h; Reflux;

Reference yield: 88.0%

: 67-56-1
methanol

: 2,2-dimethyl-5-[(oxan-4-yl)carbonyl]-1,3-dioxane-4,6-dione

: 75338-17-9
3-oxo-3-(tetrahydropyran-4-yl)propionic acid methyl ester

Guidance literature:: at 60 ℃;

Reference yield:

: 5337-03-1
tetrahydro-2H-pyran-4-carboxylic acid

: 38330-80-2
monomethyl monopotassium malonate

: 75338-17-9
3-oxo-3-(tetrahydropyran-4-yl)propionic acid methyl ester

Guidance literature:: tetrahydro-2H-pyran-4-carboxylic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 1.5h; Inert atmosphere;

monomethyl monopotassium malonate; With magnesium chloride; In tetrahydrofuran; at 20 ℃; Inert atmosphere;
DOI:10.1021/jm201331s