3-Oxabicyclo[3.1.0]hexan-2-one, (1S,5R)-

Base Information

Chemical Name:3-Oxabicyclo[3.1.0]hexan-2-one, (1S,5R)-
CAS No.:75658-86-5
Molecular Formula:C5H6O2
Molecular Weight:98.1014
Hs Code.:
DSSTox Substance ID:DTXSID30465320
Nikkaji Number:J741.159F
Wikidata:Q82291162

Synonyms:(1S,5R)-3-Oxabicyclo[3.1.0]hexan-2-one;75658-86-5;3-Oxabicyclo[3.1.0]hexan-2-one, (1S,5R)-;RAC-(1R,5S)-3-OXABICYCLO[3.1.0]HEXAN-2-ONE;DTXSID30465320;EN300-7464352

Suppliers and Price of 3-Oxabicyclo[3.1.0]hexan-2-one, (1S,5R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Oxabicyclo[3.1.0]hexan-2-one, (1S,5R)-

Chemical Property:

Boiling Point:100 °C (10 mmHg)
PSA：26.30000
Density:1.307±0.06 g/cm3(Predicted)
LogP:0.17930
XLogP3:0.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:98.036779430
Heavy Atom Count:7
Complexity:119

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2C1C(=O)OC2
Isomeric SMILES:C1[C@@H]2[C@H]1C(=O)OC2

Technology Process of 3-Oxabicyclo[3.1.0]hexan-2-one, (1S,5R)-

There total 1 articles about 3-Oxabicyclo[3.1.0]hexan-2-one, (1S,5R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 826-34-6
dimethyl cis-cyclopropane-1,2-dicarboxylate

: 75658-86-5
(1S,5R)-3-oxabicyclo[3.1.0]hexan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄

2: 68 percent / NAD⁺, FMN, pH 9, HLADH, NaOH, glycine / 120 h / 20 °C

With sodium hydroxide; lithium aluminium tetrahydride; NAD; glycine; Flavin mononucleotide;
DOI:10.1021/ja00381a024

Reference yield: 90.0%

: 75658-86-5
(1S,5R)-3-oxabicyclo[3.1.0]hexan-2-one

: 917-54-4
methyllithium

: 58479-61-1
tert-butylchlorodiphenylsilane

: 334705-96-3
2-((1S,2R)-2-{[(tert-butyldiphenylsilyl)oxy]methyl}cyclopropyl)propan-2-ol

Guidance literature:: (1S,5R)-3-oxabicyclo[3.1.0]hexan-2-one; methyllithium; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.5h;

tert-butylchlorodiphenylsilane; With 1H-imidazole; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/jo0496042

Reference yield: 89.0%

: 75658-86-5
(1S,5R)-3-oxabicyclo[3.1.0]hexan-2-one

: 917-54-4
methyllithium

: 100-39-0
benzyl bromide

: 725724-83-4
2-{(1S,2R)-2-[(benzyloxy)methyl]cyclopropyl}propan-2-ol

Guidance literature:: (1S,5R)-3-oxabicyclo[3.1.0]hexan-2-one; methyllithium; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.5h;

With sodium hydroxide; In tetrahydrofuran; diethyl ether; toluene;

benzyl bromide; With N-benzyl-N,N,N-triethylammonium chloride; In tetrahydrofuran; diethyl ether; toluene; at 20 ℃; for 20h;
DOI:10.1021/jo0496042