Naphthalene, 2-bromo-1-(phenylmethoxy)-

Base Information

• Chemical Name: Naphthalene, 2-bromo-1-(phenylmethoxy)-
• CAS No.: 76939-81-6
• Molecular Formula: C17H13BrO
• Molecular Weight: 313.194
• DSSTox Substance ID: DTXSID20445873
• Wikidata: Q82264415
• Mol file: 76939-81-6.mol

Synonyms:Naphthalene, 2-bromo-1-(phenylmethoxy)-;76939-81-6;DTXSID20445873

Chemical Property of Naphthalene, 2-bromo-1-(phenylmethoxy)-

Chemical Property:

• XLogP3: 5.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 312.01498
• Heavy Atom Count: 19
• Complexity: 274

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=C(C=CC3=CC=CC=C32)Br

Technology Process of Naphthalene, 2-bromo-1-(phenylmethoxy)-

There total 5 articles about Naphthalene, 2-bromo-1-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-bromo-1-naphthol (771-15-3) + benzyl bromide (100-39-0) → 1-(benzyloxy)-2-bromonaphthalene (76939-81-6)

Guidance literature:

With potassium carbonate; In acetone; at 56 ℃; for 21h;

DOI:10.1002/jhet.5570330460

Reference yield: 55.0%

2-diazo-1,2-naphthoquinone (879-15-2,33670-73-4) + benzyl bromide (100-39-0) → 1-(benzyloxy)-2-bromonaphthalene (76939-81-6)

Guidance literature:

With rhodium(II) pivalate; In fluorobenzene; at 20 ℃; for 18h; Inert atmosphere; Green chemistry;

DOI:10.1055/s-0035-1561295

Reference yield: 32.0%

2-bromo-1-naphthol (771-15-3) + benzyl chloride (100-44-7) → 1-(benzyloxy)-2-bromonaphthalene (76939-81-6)

Guidance literature:

With potassium carbonate; In acetonitrile; Heating;

DOI:10.1021/jo060271d

upstream raw materials:

2-bromo-1-naphthol

benzyl bromide

benzyl chloride

α-naphthol

Downstream raw materials:

1-(4-Benzyloxy-naphthalen-2-yl)-ethanone