Benzoic acid, 5-chloro-2-(dimethylamino)-

Base Information

• Chemical Name: Benzoic acid, 5-chloro-2-(dimethylamino)-
• CAS No.: 77265-65-7
• Molecular Formula: C9H10ClNO2
• Molecular Weight: 199.63400
• Mol file: 77265-65-7.mol

Synonyms:5-chloro-2-dimethylaminobenzoic acid;N.N-Dimethyl-5-chlor-anthranilsaeure;5-Chloro-2-dimethylamino-benzoic acid;5-chloro-2-(dimethylamino)benzoic acid;5-Chlor-2-dimethylamino-benzoesaeure;

Chemical Property of Benzoic acid, 5-chloro-2-(dimethylamino)-

Chemical Property:

• Melting Point: 122 - 125 °C (diethyl ether)
• PSA: 40.54000
• LogP: 2.10420

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 5-chloro-2-(dimethylamino)-

There total 5 articles about Benzoic acid, 5-chloro-2-(dimethylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

N,N-dimethyl-anthranilic acid hydrochloride (209533-97-1) → 5-chloro-2-dimethylamio-benzoic acid (77265-65-7)

Guidance literature:

With chlorine; acetic acid; In methanol; chloroform; at 0 ℃; for 0.5h;

DOI:10.1021/jm9810349

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-chloro-N,N-dimethylaniline (698-69-1) → 5-chloro-2-dimethylamino-benzyl alcohol (87066-91-9) + 5-chloro-2-dimethylamio-benzoic acid (77265-65-7)

Guidance literature:

With hydrogenchloride; at 100 ℃; im Einschlussrohr;

Reference yield:

5-chloro-2-dimethylamino-benzyl alcohol (87066-91-9) → 5-chloro-2-dimethylamio-benzoic acid (77265-65-7)

Guidance literature:

oxydiert sich leicht;

upstream raw materials:

formaldehyd

4-chloro-N,N-dimethylaniline

5-chloro-2-dimethylamino-benzyl alcohol

N,N-dimethyl-anthranilic acid hydrochloride

Downstream raw materials:

methyl 4-(2-(5-chloro-2-dimethylamino-benzoylamino)-ethyl)-benzoate