Technology Process of L-Leucine, N-[N-(N-glycylglycyl)-L-phenylalanyl]-, 1,1-dimethylethyl ester
There total 13 articles about L-Leucine, N-[N-(N-glycylglycyl)-L-phenylalanyl]-, 1,1-dimethylethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.17 h
2: 4-(aminomethyl)piperidine / CHCl3
With
benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; 4-Aminomethylpiperidine; N-ethyl-N,N-diisopropylamine;
In
chloroform;
DOI:10.1016/0040-4039(91)80176-7
- Guidance literature:
-
Multi-step reaction with 4 steps
1: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.17 h
2: 4-(aminomethyl)piperidine / CHCl3 / 0.5 h
3: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.17 h
4: 4-(aminomethyl)piperidine / CHCl3
With
benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; 4-Aminomethylpiperidine; N-ethyl-N,N-diisopropylamine;
In
chloroform;
DOI:10.1016/0040-4039(91)80176-7
- Guidance literature:
-
With
palladium diacetate; ammonium formate;
palladium on activated charcoal;
In
methanol; N,N-dimethyl-formamide;
for 7h;
Ambient temperature;
DOI:10.1021/jo00279a015
