7-Chloro-1-phenyl-1,4-dihydro-3H-2-benzopyran-3-one

Base Information

Chemical Name:7-Chloro-1-phenyl-1,4-dihydro-3H-2-benzopyran-3-one
CAS No.:77605-68-6
Molecular Formula:C₁₅H₁₁ClO₂
Molecular Weight:258.704
Hs Code.:
DSSTox Substance ID:DTXSID60508698

Synonyms:77605-68-6;7-Chloro-1-phenylisochroman-3-one;7-chloro-1-phenyl-3,4-dihydro-1H-2-benzopyran-3-one;7-Chloro-1-phenyl-1,4-dihydro-3H-2-benzopyran-3-one;DTXSID60508698

Suppliers and Price of 7-Chloro-1-phenyl-1,4-dihydro-3H-2-benzopyran-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 7-Chloro-1-phenyl-1,4-dihydro-3H-2-benzopyran-3-one

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:258.0447573
Heavy Atom Count:18
Complexity:312

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(C=C(C=C2)Cl)C(OC1=O)C3=CC=CC=C3

Technology Process of 7-Chloro-1-phenyl-1,4-dihydro-3H-2-benzopyran-3-one

There total 5 articles about 7-Chloro-1-phenyl-1,4-dihydro-3H-2-benzopyran-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41148-47-4
4-chloro-2-benzoylphenylacetic acid

: 77605-68-6
7-chloro-1-phenylisochroman-3-one

Guidance literature:: With ammonium hydroxide; copper(II) sulfate; zinc; In water; for 72h; Heating;
DOI:10.1021/jm00140a016

Reference yield:

: 59749-79-0
5-chloro-3-phenyl-1H-indene

: 77605-68-6
7-chloro-1-phenylisochroman-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / K₂Cr₂O₇, concd H₂SO₄ / H₂O / 3 h / 55 °C

2: concd NH₄OH, Zn, CuSO₄ / H₂O / 72 h / Heating

With potassium dichromate; ammonium hydroxide; sulfuric acid; copper(II) sulfate; zinc; In water;
DOI:10.1021/jm00140a016

Reference yield:

: 14548-38-0
6-chloro-1-indanone

: 77605-68-6
7-chloro-1-phenylisochroman-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Mg / 1.) benzene, THF, 45 deg C, 45 min, b) THF, benzene, 60 deg C, 2 h

2: Na₂Cr₂O₇, H₂SO₄ / H₂O / 3 h / 50 - 55 °C

3: 1.) Zn, NaOH, 2.) H₂SO₄ / 1.) ethanol, from 70 to 75 deg C, 2h

With sodium hydroxide; sodium dichromate; sulfuric acid; magnesium; zinc; In water;