41148-47-4

Upstream product

• 77948-78-8 6-chloro-3-phenyl-1H-indene 
• 2019-34-3 3-(4-chlorophenyl)propanoic acid 
• 14548-38-0 6-chloro-1-indanone 
• 59749-77-8 6-Chloro-1-phenyl-indan-1-ol 
• 59749-79-0 5-chloro-3-phenyl-1H-indene 

Downstream Products

• 126812-64-4 2-[4-Chloro-2-(hydroxy-phenyl-methyl)-phenyl]-acetamide 
• 77605-68-6 7-chloro-1-phenylisochroman-3-one 
• 21143-57-7 (2-Benzyl-4-chloro-phenyl)-acetic acid 

Relevant academic research and scientific papers

Design, synthesis and SAR of phenylamino-substituted 5,11-dihydro-dibenzo[a,d]cyclohepten-10-ones and 11H-dibenzo[b,f]oxepin-10-ones as p38 MAP kinase inhibitors

The p38 MAP kinase is a key enzyme in inflammatory diseases as it is involved in the biosynthesis of proinflammatory cytokines such as TNF-α and IL-1β. Small molecule p38 inhibitors suppress the production of these cytokines and therefore p38 is a promisi

2-(Arylmethyl)arylacetic Acids as Potential Antiinflammatory Agents

The title compounds 2 have been synthesized and tested for antiinflammatory activity.The synthetic method, consisting of the chemical sequence 3-aryl-1H-indenes (4) 2-(aroyl)arylacetic acids (5) 2, appears to be of value because of its simplicity