Ethyl 2-[methyl(diphenyl)silyl]propanoate

Base Information

Chemical Name:Ethyl 2-[methyl(diphenyl)silyl]propanoate
CAS No.:77772-22-6
Molecular Formula:C18H22O2Si
Molecular Weight:298.457
Hs Code.:
DSSTox Substance ID:DTXSID40532552
Nikkaji Number:J483.847E

Synonyms:77772-22-6;Ethyl 2-[methyl(diphenyl)silyl]propanoate;DTXSID40532552

Suppliers and Price of Ethyl 2-[methyl(diphenyl)silyl]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl 2-[methyl(diphenyl)silyl]propanoate

Chemical Property:

PSA：26.30000
LogP:2.83260
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:298.138906475
Heavy Atom Count:21
Complexity:312

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)[Si](C)(C1=CC=CC=C1)C2=CC=CC=C2
Uses Precursor to 1,1-disubstituted 1-propenes; reacts with primary Grignard reagents to give 2-(methyldiphenylsilyl)-3- alkanones, which in turn lead to regioselectively derived methyldiphenylsilyl enol ethers or to 3-alkanones; reagent for the synthesis of α-methyl-α,β-unsaturated esters.

Technology Process of Ethyl 2-[methyl(diphenyl)silyl]propanoate

There total 5 articles about Ethyl 2-[methyl(diphenyl)silyl]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 6111-99-5
ethyl diazoalaninate

: 776-76-1
methyldiphenylsilane

: 77772-22-6
Ethyl 2-(diphenylmethylsilyl)propionate

Guidance literature:: With iron(II) triflate; In dichloromethane; at 40 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.7b02488

Reference yield:

: 64-17-5
ethanol

: 201230-82-2
carbon monoxide

: 13107-13-6
methyldiphenylvinylsilane

: 77772-22-6
Ethyl 2-(diphenylmethylsilyl)propionate

: 137787-40-7
Ethyl 3-(methyldiphenylsilyl)propionate

Guidance literature:: With dicobalt octacarbonyl; In acetonitrile; at 150 ℃; under 51485.6 Torr; Yield given. Yields of byproduct given;
DOI:10.1039/c39910001247