Cyclohexanecarboxamide, N-[(dimethylamino)methyl]-1-(phenylamino)-

Base Information

• Chemical Name: Cyclohexanecarboxamide, N-[(dimethylamino)methyl]-1-(phenylamino)-
• CAS No.: 78349-37-8
• Molecular Formula: C₁₆H₂₅N₃O
• Molecular Weight: 275.394
• Mol file: 78349-37-8.mol

Synonyms:

Chemical Property of Cyclohexanecarboxamide, N-[(dimethylamino)methyl]-1-(phenylamino)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexanecarboxamide, N-[(dimethylamino)methyl]-1-(phenylamino)-

There total 2 articles about Cyclohexanecarboxamide, N-[(dimethylamino)methyl]-1-(phenylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(phenylamino)cyclohexanecarbonitrile (64269-06-3) → 1-Phenylamino-cyclohexanecarboxylic acid dimethylaminomethyl-amide (78349-37-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 62 percent / 98percent H₂SO₄ / 1) 6h, 2) 48h, room temp.

2: methanol / 1) 10 min, reflux, 2) ice-box, overnight

With sulfuric acid; In methanol;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1-anilinocyclohexane-1-carboxamide (64269-12-1) + dimethyl amine (124-40-3) → 1-Phenylamino-cyclohexanecarboxylic acid dimethylaminomethyl-amide (78349-37-8)

Guidance literature:

In methanol; Yield given; 1) 10 min, reflux, 2) ice-box, overnight;

upstream raw materials:

formaldehyd

1-anilinocyclohexane-1-carboxamide

dimethyl amine

1-(phenylamino)cyclohexanecarbonitrile

Refernces