ETHYL 2-CYANOVALERATE

Base Information

• Chemical Name: ETHYL 2-CYANOVALERATE
• CAS No.: 6967-47-1
• Molecular Formula: C8H13NO2
• Molecular Weight: 155.197
• Hs Code.: 2926909090
• Mol file: 6967-47-1.mol

Synonyms:ethyl cyanovalerate;Propylmalonsaeure-aethylester-nitril;2-cyano-valeric acid ethyl ester;2-cyanopentanoic acid ethyl ester;2-Cyan-valeriansaeure-aethylester;

Chemical Property of ETHYL 2-CYANOVALERATE

Chemical Property:

• Vapor Pressure: 0.192mmHg at 25°C
• Boiling Point: 210.5°Cat760mmHg
• Flash Point: 88°C
• PSA: 50.09000
• Density: 0.983g/cm³
• LogP: 1.48938

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2-Cyanovalerate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 2-CYANOVALERATE

There total 4 articles about ETHYL 2-CYANOVALERATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

propan-1-ol (71-23-8) + diethylazodicarboxylate (1972-28-7,218603-74-8) → ethyl 2-cyanopentanoate (6967-47-1) + ethyl 2-cyano-2-propylpentanoate (66546-90-5) + diethyl 1-(propyl)hydrazine-1,2-dicarboxylate

Guidance literature:

With ethyl 2-cyanoacetate; triphenylphosphine; In tetrahydrofuran; at -20 - 20 ℃; for 18h;

DOI:10.1246/bcsj.54.2107

Reference yield: 12.0%

propan-1-ol (71-23-8) + ethyl 2-cyanoacetate (105-56-6) → ethyl 2-cyanopentanoate (6967-47-1) + ethyl 2-cyano-2-propylpentanoate (66546-90-5) + diethyl 1-(propyl)hydrazine-1,2-dicarboxylate

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at -20 - 20 ℃; for 18h;

DOI:10.1246/bcsj.54.2107

Reference yield:

ethyl 2-cyanoacetate (105-56-6) → ethyl 2-cyanopentanoate (6967-47-1) + ethyl 2-cyano-2-propylpentanoate (66546-90-5)

Guidance literature:

With sodium ethanolate; In ethanol; at 20 ℃; for 3h;

DOI:10.1016/S0014-827X(01)01181-8

upstream raw materials:

propan-1-ol

ethyl 2-cyanoacetate

diethylazodicarboxylate

Adipic acid

Downstream raw materials:

2-aminopentanoic acid

2-Cyan-pentansaeureamid

5-n-butyl-1H-tetrazole

pentanonitrile