[R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester

Base Information

• Chemical Name: [R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester
• CAS No.: 80795-00-2
• Molecular Formula: C49H81O8P
• Molecular Weight: 829.13600
• Mol file: 80795-00-2.mol

Synonyms:Hexadecanoic acid (R)-2-(bis-benzyloxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester;

Chemical Property of [R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester

Chemical Property:

• PSA: 107.17000
• LogP: 14.96230

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester

There total 3 articles about [R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

1,2-dipalmitoyl-sn-glycero-3-phosphatidic acid (7091-44-3) + phenyldiazomethane (908094-04-2) → dibenzyl 1,2-dipalmitoyl-sn-glycero-3-phosphate (80795-00-2)

Guidance literature:

In chloroform;

DOI:10.1021/ja00315a049

Reference yield: 10.0%

1,2-dipalmitoyl-3-sn-phosphatidylethanolamine (923-61-5,3026-45-7) + phenyldiazomethane (908094-04-2) → dibenzyl 1,2-dipalmitoyl-sn-glycero-3-phosphate (80795-00-2)

Guidance literature:

In diethyl ether; chloroform; for 96h; Ambient temperature;

DOI:10.1021/ja00315a049

Reference yield:

1,2-dipalmitoyl-sn-glycerol (30334-71-5) + benzyl alcohol (100-51-6,185532-71-2) → dibenzyl 1,2-dipalmitoyl-sn-glycero-3-phosphate (80795-00-2)

Guidance literature:

With triethylamine; trichlorophosphate; Multistep reaction; 1.) chloroform, 0 deg C, 1 h, 2.) room temperature, 12 h;

DOI:10.1021/ja00315a049

upstream raw materials:

1,2-dipalmitoyl-sn-glycero-3-phosphatidic acid

phenyldiazomethane

1,2-dipalmitoyl-3-sn-phosphatidylethanolamine

1,2-dipalmitoyl-sn-glycerol

Downstream raw materials:

dibenzyl 2-palmitoyl-sn-glicero-3-phosphate

1-phospho-2-palmitoyl-(R)-propane-1,2-diol dibenzyl ester

Refernces