2,6-Dimethoxyisonicotinic acid

Base Information

Chemical Name:2,6-Dimethoxyisonicotinic acid
CAS No.:6274-82-4
Molecular Formula:C8H9 N O4
Molecular Weight:183.164
Hs Code.:2933399090
NSC Number:37478
DSSTox Substance ID:DTXSID30284497
Wikidata:Q82019470
Mol file:6274-82-4.mol

Synonyms:2,6-Dimethoxyisonicotinic acid;6274-82-4;2,6-dimethoxypyridine-4-carboxylic acid;4-Pyridinecarboxylic acid, 2,6-dimethoxy-;MFCD18257556;2,6-dimethoxyisonicotinicacid;SCHEMBL668838;2,6-Dimethoxy-isonicotinic acid;DTXSID30284497;NSC37478;NSC-37478;AKOS016006730;AB74948;SY112724;TS-00218;CS-0150236;EN300-322928;F20162;A868371;Z1255438074

Suppliers and Price of 2,6-Dimethoxyisonicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,6-Dimethoxyisonicotinicacid
50mg
$ 65.00

TRC
2,6-Dimethoxyisonicotinicacid
10mg
$ 45.00

Crysdot
2,6-Dimethoxyisonicotinicacid 98%
5g
$ 772.00

Crysdot
2,6-Dimethoxyisonicotinicacid 98%
1g
$ 250.00

Chemenu
2,6-dimethoxyisonicotinicacid 98%
1g
$ 236.00

Chemenu
2,6-dimethoxyisonicotinicacid 98%
5g
$ 729.00

AOBChem
2,6-Dimethoxypyridine-4-carboxylicacid 95%
25g
$ 2279.00

American Custom Chemicals Corporation
2,6-DIMETHOXYISONICOTINIC ACID 95.00%
5MG
$ 500.46

Ambeed
2,6-Dimethoxyisonicotinicacid 98%
5g
$ 531.00

Ambeed
2,6-Dimethoxyisonicotinicacid 98%
1g
$ 204.00

Total 34 raw suppliers

Chemical Property of 2,6-Dimethoxyisonicotinic acid

Chemical Property:

Vapor Pressure:8.4E-07mmHg at 25°C
Boiling Point:390.6°C at 760 mmHg
Flash Point:190°C
PSA：68.65000
Density:1.279g/cm³
LogP:0.79700
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:183.05315777
Heavy Atom Count:13
Complexity:173

Purity/Quality:

99% ^*data from raw suppliers

2,6-Dimethoxyisonicotinicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=N1)OC)C(=O)O

Technology Process of 2,6-Dimethoxyisonicotinic acid

There total 4 articles about 2,6-Dimethoxyisonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 67-56-1
methanol

: 124-41-4
sodium methylate

: 5398-44-7
2,6-dichloropyridine-4-carboxylic acid

: 6274-82-4
2,6-dimethoxypyridine-4-carboxylic acid

Guidance literature:: at 130 ℃; for 18h;
DOI:10.3390/molecules25061423

Reference yield: 66.4%

: 124-41-4
sodium methylate

: 5398-44-7
2,6-dichloropyridine-4-carboxylic acid

: 6274-82-4
2,6-dimethoxypyridine-4-carboxylic acid

Guidance literature:: In diethylene glycol dimethyl ether; for 24h; Reflux; Dean-Stark;
DOI:10.1016/j.bioorg.2020.103755

Reference yield:

: 67-56-1
methanol

: 5398-44-7
2,6-dichloropyridine-4-carboxylic acid

: 15855-06-8
2-chloro-6-methoxy-isonicotinic acid

: 6274-82-4
2,6-dimethoxypyridine-4-carboxylic acid

Guidance literature:: methanol; 2,6-dichloropyridine-4-carboxylic acid; With sodium hydroxide; for 0.5h; Heating / reflux;

With hydrogenchloride; In water; pH=4 - 6;