Pyridazine, 1-benzoyl-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,4,5,6-tetrahydro-, (5S)-

Base Information

Chemical Name:Pyridazine, 1-benzoyl-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,4,5,6-tetrahydro-, (5S)-
CAS No.:821806-80-8
Molecular Formula:C17H26N2O2Si
Molecular Weight:318.48600
Hs Code.:

Synonyms:[(S)-5-(tert-Butyl-dimethyl-silanyloxy)-5,6-dihydro-4H-pyridazin-1-yl]-phenyl-methanone;

Suppliers and Price of Pyridazine, 1-benzoyl-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,4,5,6-tetrahydro-, (5S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Pyridazine, 1-benzoyl-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,4,5,6-tetrahydro-, (5S)-

Chemical Property:

PSA：41.90000
LogP:3.28220

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Pyridazine, 1-benzoyl-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,4,5,6-tetrahydro-, (5S)-

There total 2 articles about Pyridazine, 1-benzoyl-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,4,5,6-tetrahydro-, (5S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 909730-49-0
(S)-5-(tert-butyldimethylsilyloxy)-1,4,5,6-tetrahydropyridazine

: 98-88-4
benzoyl chloride

: 821806-80-8
(S)-1-benzoyl-5-(tert-butyldimethylsilyloxy)-1,4,5,6-tetrahydropyridazine

Guidance literature:: With pyridine; at 0 - 23 ℃;
DOI:10.1016/j.tetasy.2006.06.004

Reference yield:

: 169522-70-7
(S)-3-<(tert-butyldimethylsilyl)oxy>-4-(tosyloxy)butanal

: 821806-80-8
(S)-1-benzoyl-5-(tert-butyldimethylsilyloxy)-1,4,5,6-tetrahydropyridazine

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / hydrazine monohydrate / ethanol / 0 - 23 °C

2: 98 percent / pyridine / 0 - 23 °C

With pyridine; hydrazine hydrate; In ethanol;
DOI:10.1016/j.tetasy.2006.06.004

Reference yield:

: 821806-80-8
(S)-1-benzoyl-5-(tert-butyldimethylsilyloxy)-1,4,5,6-tetrahydropyridazine

: 7677-24-9
trimethylsilyl cyanide

: (3R,5S)-1-benzoyl-5-(tert-butyldimethylsilyloxy)-hexahydropyridazine-3-carbonitrile

: 821806-82-0
(3S,5S)-1-benzoyl-5-(tert-butyldimethylsilyloxy)-hexahydropyridazine-3-carbonitrile

Guidance literature:: With sodium acetate; zinc trifluoromethanesulfonate; acetic acid; at 0 - 23 ℃; for 24h;
DOI:10.1016/j.tetasy.2006.06.004