Butanoic acid, 3-oxo-, (2E)-2-butenyl ester

Base Information

• Chemical Name: Butanoic acid, 3-oxo-, (2E)-2-butenyl ester
• CAS No.: 82259-92-5
• Molecular Formula: C8H12O3
• Molecular Weight: 156.181
• Mol file: 82259-92-5.mol

Synonyms:

Chemical Property of Butanoic acid, 3-oxo-, (2E)-2-butenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Butanoic acid, 3-oxo-, (2E)-2-butenyl ester

There total 3 articles about Butanoic acid, 3-oxo-, (2E)-2-butenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(E/Z)-2-buten-1-ol (6117-91-5,542-72-3) + ethyl acetoacetate (141-97-9) → but-2-enyl 3-oxobutanoate (82259-92-5,31041-83-5)

Guidance literature:

With triethylamine; In toluene; at 110 ℃; for 10h;

DOI:10.1080/00397911.2014.932812

Reference yield: 80.0%

(E/Z)-2-buten-1-ol (6117-91-5,542-72-3) + acetoacetic acid methyl ester (105-45-3) → but-2-enyl 3-oxobutanoate (82259-92-5,31041-83-5)

Guidance literature:

With natural kaolinitic clay; In toluene; for 8h; Heating; further reagent: Montmorillonite K₁₀ clay;

DOI:10.1021/jo971404l

Reference yield:

4-methyleneoxetan-2-one (674-82-8,2130-41-8) + (E/Z)-2-buten-1-ol (6117-91-5,542-72-3) → but-2-enyl 3-oxobutanoate (82259-92-5,31041-83-5)

Guidance literature:

With crotonic acid sodium salt; at 0 - 5 ℃;

DOI:10.1021/ja01250a049

upstream raw materials:

4-methyleneoxetan-2-one

(E/Z)-2-buten-1-ol

acetoacetic acid methyl ester

ethyl acetoacetate

Downstream raw materials:

trans-2-buten-1-yl diazoacetate

methyl (1S,2R,3R)-2-hydroxymethyl-3-methylcyclopropane-1-carboxylate

methyl (1S,2S,3R)-2-formyl-3-methylcyclopropane-1-carboxylate

methyl (1S,2R,3R)-2-formyl-3-methylcyclopropane-1-carboxylate

Refernces

• 1、 Gohain, Mukut,Kumar, Vinod,Van Tonder, Johannes H.,Swart, Hendrik C.,Ntwaeaborwa, Odireleng M.,Bezuidenhoudt, Barend C. B.. "Nano CuFe2O4: An efficient, magnetically separable catalyst for transesterification of β-ketoesters". . p. 18972 - 18976. Retrieved 2015/03/04.
• 2、 Ponde, Datta E.,Deshpande, Vishnu H.,Bulbule, Vivek J.,Sudalai, Ammugam,Gajare, Anil S.. "Selective Catalytic Transesterification, Transthiolesterification, and Protection of Carbonyl Compounds over Natural Kaolinitic Clay". . p. 1058 - 1063. Retrieved 2007/10/03.