2-(3-Chloro-2-methoxyphenyl)acetonitrile

Base Information

Chemical Name:2-(3-Chloro-2-methoxyphenyl)acetonitrile
CAS No.:825654-87-3
Molecular Formula:C9H8ClNO
Molecular Weight:181.622
Hs Code.:
DSSTox Substance ID:DTXSID70591990
Wikidata:Q82485872

Synonyms:2-(3-chloro-2-methoxyphenyl)acetonitrile;825654-87-3;SCHEMBL3531950;3-Chloro-2-methoxybenzylcyanide;DTXSID70591990;ASVPOCGEQKGLQQ-UHFFFAOYSA-N;(3-Chloro-2-methoxyphenyl)acetonitrile;EN300-1983429

Suppliers and Price of 2-(3-Chloro-2-methoxyphenyl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(3-Chloro-2-methoxyphenyl)acetonitrile

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:181.0294416
Heavy Atom Count:12
Complexity:186

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC=C1Cl)CC#N

Technology Process of 2-(3-Chloro-2-methoxyphenyl)acetonitrile

There total 2 articles about 2-(3-Chloro-2-methoxyphenyl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 773837-37-9
sodium cyanide

: 1044256-94-1
1-(bromomethyl)-3-chloro-2-methoxybenzene

: 825654-87-3
2-(3-chloro-2-methoxyphenyl)acetonitrile

Guidance literature:: In ethanol; water; at 100 ℃; for 3h; Inert atmosphere;

Reference yield:

: 3438-15-1
3-chloro-2-methoxy-1-methylbenzene

: 825654-87-3
2-(3-chloro-2-methoxyphenyl)acetonitrile

Guidance literature:: 3-chloro-2-methoxy-1-methylbenzene; With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 16h; Heating / reflux;

With potassium cyanide; In DMF (N,N-dimethyl-formamide); water; at 0 ℃; for 16h;

Reference yield: 69.2%

: 825654-87-3
2-(3-chloro-2-methoxyphenyl)acetonitrile

: 106-93-4
ethylene dibromide

: 879339-40-9
1-(3-chloro-2-methoxyphenyl)-cyclopropanecarbonitrile

Guidance literature:: 2-(3-chloro-2-methoxyphenyl)acetonitrile; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

ethylene dibromide; In N,N-dimethyl-formamide; at 20 ℃;