Benzamide, N-[2-(dimethylamino)ethyl]-N-(2-iodophenyl)-2-nitro-

Base Information

Chemical Name:Benzamide, N-[2-(dimethylamino)ethyl]-N-(2-iodophenyl)-2-nitro-
CAS No.:826991-64-4
Molecular Formula:C17H18IN3O3
Molecular Weight:439.253
Hs Code.:
DSSTox Substance ID:DTXSID00479555
Wikidata:Q82313656

Synonyms:826991-64-4;Benzamide, N-[2-(dimethylamino)ethyl]-N-(2-iodophenyl)-2-nitro-;DTXSID00479555

Suppliers and Price of Benzamide, N-[2-(dimethylamino)ethyl]-N-(2-iodophenyl)-2-nitro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Benzamide, N-[2-(dimethylamino)ethyl]-N-(2-iodophenyl)-2-nitro-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:439.03929
Heavy Atom Count:24
Complexity:441

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)CCN(C1=CC=CC=C1I)C(=O)C2=CC=CC=C2[N+](=O)[O-]

Technology Process of Benzamide, N-[2-(dimethylamino)ethyl]-N-(2-iodophenyl)-2-nitro-

There total 3 articles about Benzamide, N-[2-(dimethylamino)ethyl]-N-(2-iodophenyl)-2-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 34489-87-7
N-(2-iodo-phenyl)-2-nitro-benzamide

: 107-99-3
2-(dimethylamino)ethyl chloride

: 826991-64-4
N-(2-iodo-phenyl)-N-(2-dimethylamino-ethyl)-2-nitro-benzamide

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; In benzene; at 70 - 80 ℃; for 12h;
DOI:10.1016/j.tet.2004.10.061

Reference yield:

: 615-43-0
2-iodophenylamine

: 826991-64-4
N-(2-iodo-phenyl)-N-(2-dimethylamino-ethyl)-2-nitro-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / triethylamine / CH₂Cl₂ / 5 h / 20 °C

2: 98 percent / NaOH; K₂CO₃; tetrabutylammonium hydrogen sulphate / benzene / 12 h / 70 - 80 °C

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; triethylamine; In dichloromethane; benzene;
DOI:10.1016/j.tet.2004.10.061

Reference yield:

: 610-14-0
2-nitrobenzyl chloride

: 826991-64-4
N-(2-iodo-phenyl)-N-(2-dimethylamino-ethyl)-2-nitro-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / triethylamine / CH₂Cl₂ / 5 h / 20 °C

2: 98 percent / NaOH; K₂CO₃; tetrabutylammonium hydrogen sulphate / benzene / 12 h / 70 - 80 °C

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; triethylamine; In dichloromethane; benzene;
DOI:10.1016/j.tet.2004.10.061