4-HYDROXY-3-NITROBENZOPHENONE

Base Information

• Chemical Name: 4-HYDROXY-3-NITROBENZOPHENONE
• CAS No.: 5464-98-2
• Molecular Formula: C13H9 N O4
• Molecular Weight: 243.219
• Hs Code.: 2914700090
• Mol file: 5464-98-2.mol

Synonyms:Benzophenone,4-hydroxy-3-nitro- (6CI,8CI); 4-Benzoyl-2-nitrophenol;4-Hydroxy-3-nitrobenzophenone; NSC 26791

Chemical Property of 4-HYDROXY-3-NITROBENZOPHENONE

Chemical Property:

• Vapor Pressure: 4.6E-07mmHg at 25°C
• Melting Point: 92-93°C
• Refractive Index: 1.5880 (estimate)
• Boiling Point: 402.8°Cat760mmHg
• PKA: 5.16±0.14(Predicted)
• Flash Point: 172.4°C
• PSA: 83.12000
• Density: 1.367g/cm³
• LogP: 3.05460

Purity/Quality:

98% ^*data from raw suppliers

4-HYDROXY-3-NITROBENZOPHENONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-HYDROXY-3-NITROBENZOPHENONE

There total 8 articles about 4-HYDROXY-3-NITROBENZOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-Hydroxybenzophenone (1137-42-4) → (4-hydroxy-3-nitrophenyl)(phenyl)methanone (5464-98-2)

Guidance literature:

With sodium nitrate; potassium hydrogensulfate; silica gel; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1007/s00044-017-1824-y

Reference yield: 70.0%

3,4-dichlorobenzophenone (6284-79-3) → (3-chloro-4-hydroxyphenyl)(phenyl)methanone (55191-20-3) + (4-hydroxy-3-nitrophenyl)(phenyl)methanone (5464-98-2)

Guidance literature:

With sodium nitrite; In dimethyl sulfoxide; at 170 ℃; for 10h;

DOI:10.1055/s-1992-26192

Reference yield: 60.0%

2-nitro-4-benzylphenol (37021-63-9) → (4-hydroxy-3-nitrophenyl)(phenyl)methanone (5464-98-2)

Guidance literature:

With oxygen; cobalt(II) diacetate tetrahydrate; sodium hydroxide; In ethylene glycol; at 100 ℃; for 15h; under 760.051 Torr;

DOI:10.1007/s11164-014-1801-8

upstream raw materials:

4-benzoyl-N-methyl-2-nitroaniline

4-bromo-3-nitrobenzophenone

4-methoxy-3-nitro-benzophenone

4-Hydroxybenzophenone

Downstream raw materials:

(3-amino-4-hydroxy-phenyl)-phenyl-methanone

3-benzoylamino-4-hydroxybenzophenone

(2-phenyl-5-benzoxazolyl)phenylmethanone

Refernces

• 1、 Jadhav, Amol G.,Shinde, Suvidha S.,Lanke, Sandip K.,Sekar, Nagaiyan. "Benzophenone based fluorophore for selective detection of Sn2?+ ion: Experimental and theoretical study". . p. 291 - 296. Retrieved 2016/12/18.
• 2、 Chehardoli, Gholamabbas,Zolfigol, Mohammad Ali,Azimi, Seyedeh Bahareh,Alizadeh, Ebadollah. "Melamine-(H2SO4)3 and PVP-(H 2SO4)n as solid acids: Synthesis and application in the first mono- and di-nitration of bisphenol A and other phenols". experimental part. p. 827 - 830. Retrieved 2012/02/14.