Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Base Information

Chemical Name:Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS No.:5948-72-1
Molecular Formula:C12H14N2O3S
Molecular Weight:0
Hs Code.:2934999090
NSC Number:332465
DSSTox Substance ID:DTXSID10318527
Nikkaji Number:J885.747D
ChEMBL ID:CHEMBL1371053
Mol file:5948-72-1.mol

Synonyms:5948-72-1;ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate;6-Methyl-2-oxo-4-thiophen-2-yl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester;ethyl 2-hydroxy-4-methyl-6-(2-thienyl)-1,6-dihydro-5-pyrimidinecarboxylate;ethyl 6-methyl-2-oxo-4-thiophen-2-yl-3,4-dihydro-1H-pyrimidine-5-carboxylate;MFCD00124780;Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate;NSC332465;Oprea1_433973;Oprea1_766582;MLS000711148;SCHEMBL3003016;CHEMBL1371053;DTXSID10318527;HMS2639A04;HMS3360C17;CCG-1550;STK396795;STK868207;AKOS000655121;AKOS003325710;AKOS016294620;ethyl 4-methyl-2-oxo-6-(2-thienyl)-1,3,6-trihydropyrimidine-5-carboxylate;NSC 332465;NSC-332465;SMR000280915;AT-057/40723569;SR-01000399622;SR-01000399622-1;SR-01000399622-2;Z47751402;F0095-1730;2-Oxo-4-(2-thienyl)-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester;6-methyl-2-oxo-4-thiophen-2-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester;ethyl 2-hydroxy-4-methyl-6-(thiophen-2-yl)-1,6-dihydropyrimidine-5-carboxylate;Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate;Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate #

Suppliers and Price of Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 8 raw suppliers

Chemical Property of Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Chemical Property:

Vapor Pressure:2.04E-06mmHg at 25°C
Boiling Point:394°C at 760 mmHg
Flash Point:192.1°C
PSA：95.67000
Density:1.255g/cm³
LogP:2.59670
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:266.07251349
Heavy Atom Count:18
Complexity:395

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(NC(=O)NC1C2=CC=CS2)C

Technology Process of Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

There total 13 articles about Ethyl 6-methyl-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 98-03-3
thiophene-2-carbaldehyde

: 141-97-9
ethyl acetoacetate

: 57-13-6
urea

: 5948-72-1
ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Guidance literature:: With 1-methyl-3-(3-trimethoxysilylpropyl) imidazolium hydrogen sulfate immobilized on magnetic Fe₃O₄ nanoparticles; In neat (no solvent); at 100 ℃; for 0.416667h; Catalytic behavior;
DOI:10.1039/c3nj01065a