4(1H)-Quinolinone, 1-phenyl-2-(trifluoromethyl)-

Base Information

Chemical Name:4(1H)-Quinolinone, 1-phenyl-2-(trifluoromethyl)-
CAS No.:837364-35-9
Molecular Formula:C16H10F3NO
Molecular Weight:289.257
Hs Code.:
DSSTox Substance ID:DTXSID50477667
Wikidata:Q82310491

Synonyms:837364-35-9;4(1H)-Quinolinone, 1-phenyl-2-(trifluoromethyl)-;1-phenyl-2-(trifluoromethyl)quinolin-4(1H)-one;1-PHENYL-2-TRIFLUOROMETHYL-4(1H)-QUINOLONE;1-PHENYL-2-(TRIFLUOROMETHYL)QUINOLIN-4-ONE;DTXSID50477667;NYUGPFRJWDZBOW-UHFFFAOYSA-N;MFCD07779983;AKOS025212620;1-Phenyl-2-trifluoromethyl-4-quinolone

Suppliers and Price of 4(1H)-Quinolinone, 1-phenyl-2-(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4(1H)-Quinolinone, 1-phenyl-2-(trifluoromethyl)-

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:289.07144843
Heavy Atom Count:21
Complexity:437

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C3=CC=CC=C3C(=O)C=C2C(F)(F)F

Technology Process of 4(1H)-Quinolinone, 1-phenyl-2-(trifluoromethyl)-

There total 2 articles about 4(1H)-Quinolinone, 1-phenyl-2-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 383-63-1
ethyl trifluoroacetate,

: 23699-74-3
1-(2-anilinophenyl)ethan-1-one

: 837364-35-9
1-phenyl-2-(trifluoromethyl)quinolin-4(1H)-one

Guidance literature:: With lithium hydride; In tetrahydrofuran; for 1h; Heating;
DOI:10.1016/j.jfluchem.2004.04.010

Reference yield:

: 91-40-7
2-(phenylamino)benzoic acid

: 837364-35-9
1-phenyl-2-(trifluoromethyl)quinolin-4(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: LiH / tetrahydrofuran / 0.5 h / Heating

1.2: 81 percent / tetrahydrofuran; diethyl ether / 4 h / 20 °C

2.1: 90 percent / LiH / tetrahydrofuran / 1 h / Heating

With lithium hydride; In tetrahydrofuran;
DOI:10.1016/j.jfluchem.2004.04.010